사만다린

사만다린
사만다린 구조식 이미지
카스 번호:
467-51-6
한글명:
사만다린
동의어(한글):
사만다린
상품명:
SAMANDARINE
동의어(영문):
Samandarin;SAMANDARINE;1α,4α-Epoxy-3-aza-A-homo-5β-androstan-16β-ol;2,5-Epoxycyclopenta[5,6]naphth[1,2-d]azepin-9-ol, octadecahydro-5a,7a-dimethyl-, (2S,5R,5aS,5bS,7aR,9S,10aS,10bS,12aR)-
CBNumber:
CB21432361
분자식:
C19H31NO2
포뮬러 무게:
305.45
MOL 파일:
467-51-6.mol

사만다린 속성

녹는점
187-188°
알파
D17 +43.3° (acetone)
끓는 점
427.9±40.0 °C(Predicted)
밀도
1.111±0.06 g/cm3(Predicted)
산도 계수 (pKa)
15.26±0.60(Predicted)
optical activity
+43.317 (c 0.842, acetone)

안전

사만다린 C화학적 특성, 용도, 생산

개요

This pentacyclic alkaloid also occurs in the skin secretion of Salamandra species, particularly S. atra and S. maculosa. It forms colourless crystals from a variety of solvents but when crystallized from MeOH contains solvent of crystallization. The solutions are strongly alkaline and the base is dextrorotatory with [α]17D + 43.7°. Two bridge methyl groups, a non-phenolic hydroxyl group and a methylimino group are present in the molecule. Several crystalline derivatives have been prepared including the hydrochloride, m.p. 32l-2°C; the O,N-diacetyl derivative, m.p. l67-8°C; the monoformyl compound, m.p. l48-ISOoC; diformyl derivative, m.p. 2S6-g0C; N-nitroso compound, m.p. 164-5°C and the N-methyl derivative which is characterized as the hydrochloride, m.p. 300-2°C (dec.) and the methiodide, m.p. 27l-2°C.

참고 문헌

Schopf, Braun., Annalen., 514,69 (1934)
Schopf, Koch., ibid, 552,62 (1942)
Wolfeletal., Ber., 94, 2361 (1961)

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