3''-METHOXYOROBOL

3''-METHOXYOROBOL 구조식 이미지
카스 번호:
36190-95-1
상품명:
3''-METHOXYOROBOL
동의어(영문):
-O-Methylorobol;3'-Methoxy-4',5,7-trihydroxyisoflavone;5,7-Dihydroxy-3-(4-hydroxy-3-methoxyphenyl)-4H-chromen-4-one;4H-1-Benzopyran-4-one, 5,7-dihydroxy-3-(4-hydroxy-3-methoxyphenyl)-
CBNumber:
CB21484744
분자식:
C16H12O6
포뮬러 무게:
300.26
MOL 파일:
36190-95-1.mol

3''-METHOXYOROBOL 속성

안전

3''-METHOXYOROBOL C화학적 특성, 용도, 생산

용도

3''-Methoxy-4'',5,7-trihydroxyisoflavone is a derivative of Genistein (G350000); a compound that exhibits specific inhibitory activity against tyrosine kinases, including autophosphorylation of epidermal growth factor receptor kinase (IC50 - 2.6uM). Also inhibits other protein kinases through competitive inhibition of ATP. Inhibits tumor cell proliferation and induces tumor cell differentiation. Produces cell-cycle arrest and apoptosis in Jurat T-leukemia cells. However, it prevents anti-CD3 monoclonal antibody-induced thymic apoptosis. Genistein also inhibits topoisomerase II activity in vitro. Genistein has also been shown to inhibit the action of GABA on recombinant GABAA receptors 2.

3''-METHOXYOROBOL 준비 용품 및 원자재

원자재

준비 용품


3''-METHOXYOROBOL 공급 업체

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