Anti-GOK, Anti-Stromal interaction molecule I

Anti-GOK, Anti-Stromal interaction molecule I C화학적 특성, 용도, 생산

용도

Anti-STIM1 (N-terminal) antibody produced in rabbit has been used in:

• western blotting
• immunoprecipitation
• immunofluorescence

일반 설명

STIM1 (stromal interaction molecule 1) is a conserved single-pass transmembrane protein, which is expressed ubiquitously in a wide variety of human primary and transformed cell types. STIM1 is modified by phosphorylation and N-linked glycosylation. STIM1 localized predominantly in the membrane of the endoplasmic reticulum (ER). It contains an N-terminal EF hand motif located in the ER lumen and appears to function as a sensor of ER Ca²⁺ levels.

Biochem/physiol Actions

STIM1 (stromal interaction molecule 1) is required for the activation of store-operated Ca2+ influx. Overexpression of STIM1 and Orai1 markedly increases the calcium release-activated calcium (CRAC) current (I-CRAC).

Anti-GOK, Anti-Stromal interaction molecule I 준비 용품 및 원자재

원자재

준비 용품

Anti-GOK, Anti-Stromal interaction molecule I 공급 업체

공급자	전화	이메일	국가	제품 수	이점
SIGMA-RBI	--		Switzerland	6913	91