비스클로로안트라벤족소시논

비스클로로안트라벤족소시논
비스클로로안트라벤족소시논 구조식 이미지
카스 번호:
866022-28-8
한글명:
비스클로로안트라벤족소시논
동의어(한글):
비스클로로안트라벤족소시논
상품명:
Bischloroanthrabenzoxocinone
동의어(영문):
BABX;Bischloroanthrabenzoxocinone;6,16-Epoxy-14H-anthra[2,3-d][1]benzoxocin-14-one, 10,12-dichloro-6,7,9,16-tetrahydro-11,13,15-trihydroxy-3-methoxy-1,6,9,9-tetramethyl-, (6R,16R)-
CBNumber:
CB22533948
분자식:
C28H24Cl2O7
포뮬러 무게:
543.392
MOL 파일:
866022-28-8.mol

비스클로로안트라벤족소시논 속성

녹는점
167-169 °C(Solv: nitromethane (75-52-5))
끓는 점
660.1±55.0 °C(Predicted)
밀도
1.475±0.06 g/cm3(Predicted)
저장 조건
Store at -20°C
용해도
DMF: soluble; DMSO: soluble; Ethanol: soluble; Methanol: soluble
산도 계수 (pKa)
4.60±0.60(Predicted)

안전

HS 번호 29419000

비스클로로안트라벤족소시논 C화학적 특성, 용도, 생산

용도

Bischloroanthrabenzoxocinone ((-)BABX) is a selective inhibitor of Type II fatty acid synthesis (FASII). BABX showed IC50 values of 11.4 and 35.3 μg/ml in the S. aureus and E. coli FASII assays, respectively, with comparable antibacterial activities. Type II fatty acid synthesis (FASII) is essential to bacterial cell viability and is a promising target for the development of novel antibiotics. More recently, BABX has been shown to inhibit agonist binding to Liver X receptors (LXR). The receptors regulate the expression of the ABCA1 gene, which mediates the efflux of cholesterol from cells.

비스클로로안트라벤족소시논 준비 용품 및 원자재

원자재

준비 용품


비스클로로안트라벤족소시논 공급 업체

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