GPR55 Polyclonal Antibody
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GPR55 Polyclonal Antibody 속성
안전
GPR55 Polyclonal Antibody C화학적 특성, 용도, 생산
개요
GPR55 is an orphan G protein-coupled receptor. GPR55 is expressed in the brain, large dorsal root ganglion neurons, and many peripheral tissues. Endogenous agonists for GPR55 include lysophosphatidylinositol (EC50 = 1.2 μM in a β-arrestin-GFP biosensor assay) and the endocannabinoids anandamide (arachidonoyl ethanolamide; ) and 2-arachidonoyl glycerol (; EC50s = 18.4 and 3.5 nM in GTPγS binding assays). It is also activated by the cannabinoid Δ9-tetrahydrocannabinol (Δ9-THC; EC50 = 8 nM in a GTPγS binding assay). GPR55 is expressed in β cells and pharmacological activation increases glucose-induced insulin release in wild-type mice and, to a lesser extent, in Gpr55 knockout mice. GPR55 expression is increased in the visceral adipose tissue of obese patients and, to a larger extent, in obese patients with type-2 diabetes. Activation of GPR55 increases the growth and invasiveness of cancer cells in vitro, and its expression in patient-derived tumors is positively correlated with a worse prognosis. GPR55 activation has also been associated with inhibition of osteoclast formation. Cayman’s GPR55 Polyclonal Antibody can be used for flow cytometry, immunofluorescence, and Western blot applications. The antibody recognizes GPR55 at 37 kDa from human and bovine samples. Post-translational modifications such as glycosylation may retard receptor electrophoretic migration such that the protein signal may be detected above 37 kDa.GPR55 Polyclonal Antibody 준비 용품 및 원자재
원자재
준비 용품
GPR55 Polyclonal Antibody 공급 업체
글로벌( 19)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| Rhenbo (Shanghai) Biochemical Technology Co., Ltd. | -- |
CHINA | 6334 | 58 | |
| Shanghai Haoran Biotechnology Co., Ltd. | -- |
470003480@QQ.COM | CHINA | 6968 | 58 |
| Beijing Luyuan Bird Biotechnology Co., Ltd. | -- |
15810802415@139.com | CHINA | 6757 | 58 |
| Kelu (Wuhan) Biotechnology Co., Ltd. | -- |
CHINA | 5344 | 58 | |
| Hunan Aijia Biotechnology Co., Ltd. | -- |
order@auragene.com | CHINA | 4293 | 58 |
| Shanghai Mengze Biotechnology Co., Ltd. | -- |
luxionggang@126.com | CHINA | 6393 | 58 |
| Suzhou Far East Puhui Biotechnology Co., Ltd. | -- |
2810475392@qq.com | CHINA | 5225 | 58 |
| Shanghai Jijin Chemical Technology Co., Ltd. | -- |
jijinhuaxue@sina.com | CHINA | 6617 | 58 |
| Shanghai yiji industries Co., Ltd. | -- |
yiji01@foxmail.com | China | 6294 | 50 |
| Boao Pike | -- |
lyn@biopike.com.cn | CHINA | 6629 | 58 |