니트라졸라M

니트라졸라M
니트라졸라M 구조식 이미지
카스 번호:
28910-99-8
한글명:
니트라졸라M
동의어(한글):
니트라졸라M
상품명:
Nitrazolam
동의어(영문):
NitrazolaM;Nitrazolame;Nitrazolam 98%;1-Methyl-8-nitro-6-phenyl-4H-2,3,5,10b-tetraaza-benzo[e]azulene;1-Methyl-8-nitro-6-phenyl-4H-s-triazolo[4,3-a][1,4]benzodiazepine;1-Methyl-8-nitro-6-phenyl-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine;4H-[1,2,4]Triazolo[4,3-a][1,4]benzodiazepine, 1-methyl-8-nitro-6-phenyl-;1-methyl-8-nitro-6-phenyl-4H-benzo[f][1,2,4]triazolo[4,3-a][1,4]diazepine
CBNumber:
CB22681342
분자식:
C17H13N5O2
포뮬러 무게:
319.32
MOL 파일:
28910-99-8.mol
MSDS 파일:
SDS

니트라졸라M 속성

끓는 점
550.2±60.0 °C(Predicted)
밀도
1.44±0.1 g/cm3(Predicted)
용해도
DMF: 30 mg/ml; DMF:PBS(pH 7.2)(1:1): 0.5 mg/ml; DMSO: 20 mg/ml; Ethanol: 10 mg/ml; Methanol: 1 mg/ml
산도 계수 (pKa)
1.96±0.40(Predicted)
물리적 상태
고체
물리적 상태
단단한 모양
색상
노란색
InChI
InChI=1S/C17H13N5O2/c1-11-19-20-16-10-18-17(12-5-3-2-4-6-12)14-9-13(22(23)24)7-8-15(14)21(11)16/h2-9H,10H2,1H3
InChIKey
OYRPNABWTHDOFK-UHFFFAOYSA-N
SMILES
N12C(C)=NN=C1CN=C(C1=CC=CC=C1)C1=CC([N+]([O-])=O)=CC=C12

안전

니트라졸라M C화학적 특성, 용도, 생산

개요

Nitrazolam is classified as a novel benzodiazepine, although its synthesis and activity have been previously described in the literature. Benzodiazepines are central nervous system depressants. Novel benzodiazepines, often pirated from early drug discovery or pharmaceutical studies, have appeared on the novel and illicit drug markets in recent years. These substances have caused adverse events, including deaths, as described in the literature. Nitrazolam is structurally similar to traditional benzodiazepines nitrazepam and alprazolam, Schedule IV substances in the United States, as well as the novel benzodiazepines flunitrazolam and clonazelam. 

Clinical Use

Nitrazolam is primarily used as an anticonvulsant in children. It is also still used in the most severe and debilitating cases of insomnia in an inpatient setting or in short term outpatient treatment. Hypnotic benzodiazepines estazolam and nitrazepam are used more frequently than nimetazepam for this purpose. The foremost use of Nitrazepam is to treat insomnia, which includes an inability to fall asleep and waking up at night regularly. It’s also prescribed for restless legs syndrome, anxiety disorder, and depression. 

니트라졸라M 준비 용품 및 원자재

원자재

준비 용품


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