P7C3-A20

P7C3-A20 구조식 이미지
카스 번호:
1235481-90-9
상품명:
P7C3-A20
동의어(영문):
CS-2365;P7C3-A20;P7C3-A20, >=98%;N-(3-(3,6-DIBROMO-9H-CARBAZOL-9-YL)-2-FLUOROPROPYL)-3-METHOXYANILINE;9H-Carbazole-9-propanamine, 3,6-dibromo-β-fluoro-N-(3-methoxyphenyl)-;3,6-Dibromo-beta-fluoro-N-(3-methoxyphenyl)-9H-carbazole-9-propanamine;P7C3-A20 3,6-Dibromo-beta-fluoro-N-(3-methoxyphenyl)-9H-carbazole-9-propanamine
CBNumber:
CB22686079
분자식:
C22H19Br2FN2O
포뮬러 무게:
506.21
MOL 파일:
1235481-90-9.mol

P7C3-A20 속성

끓는 점
641.3±55.0 °C(Predicted)
밀도
1.57±0.1 g/cm3(Predicted)
저장 조건
Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
용해도
DMSO에 용해됨(40mg/ml)
산도 계수 (pKa)
3.25±0.50(Predicted)
물리적 상태
고체
물리적 상태
단단한 모양
색상
회백색
안정성
제공된 대로 구매일로부터 2년 동안 안정적입니다. DMSO 용액은 -20°C에서 최대 3개월 동안 보관할 수 있습니다.

안전

P7C3-A20 C화학적 특성, 용도, 생산

개요

P7C3-A20 is a derivative of P7C3 (Item No. 16682) that has proneurogenic and neuroprotective activity. It increases proliferation in the subgranular zone (SGZ) of the adult mouse dentate gyrus in a dose-dependent manner when administered at doses ranging from 0.1 to 10 μM. It also protects U2OS cells from calcium-induced mitochondrial dissolution. In a rat model of traumatic brain injury, P7C3-A20 (10 mg/kg, i.p., twice daily for one week) decreases contusion volume, increases proliferation in the SGZ, and decreases the latency to reach the platform in the Morris water maze to sham surgery control levels. It also prevents or reverses dopaminergic cell death and motor deficits in a 6-OHDA rat model of Parkinson's disease.

P7C3-A20 준비 용품 및 원자재

원자재

준비 용품


P7C3-A20 공급 업체

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