아미노산히드록사메이트DL-세린히드록사메이트

아미노산히드록사메이트DL-세린히드록사메이트
아미노산히드록사메이트DL-세린히드록사메이트 구조식 이미지
카스 번호:
55779-32-3
한글명:
아미노산히드록사메이트DL-세린히드록사메이트
동의어(한글):
아미노산히드록사메이트DL-세린히드록사메이트
상품명:
AMINO ACID HYDROXAMATES DL-SERINE HYDROXAMATE
동의어(영문):
SHX;dl-serine hydroxamate;Propanamide, 2-amino-N,3-dihydroxy-;DL-SERINE HYDROXAMATE, SERYL-TRNA SY;(Z)-2-aMino-N,3-dihydroxypropaniMidic acid;AMINO ACID HYDROXAMATES DL-SERINE HYDROXAMATE;rac-(R*)-2-Amino-3-hydroxypropanehydroxamic acid;DL-Serine hydroxaMate seryl-tRNA synthetase inhibitor
CBNumber:
CB2281528
분자식:
C3H8N2O3
포뮬러 무게:
120.11
MOL 파일:
55779-32-3.mol
MSDS 파일:
SDS

아미노산히드록사메이트DL-세린히드록사메이트 속성

저장 조건
-20°C
물리적 상태
Solid
색상
White to off-white

안전

WGK 독일 3

아미노산히드록사메이트DL-세린히드록사메이트 C화학적 특성, 용도, 생산

용도

Serine has been used as an inhibitor of seryl-tRNA synthetase. DL-Serine hydroxamate is used to induce metabolic synthesis of guanosine 3′-diphosphate 5′-diphosphate (ppGpp) in E. coli by amino acid starvation. It is also used to synchronize cell cycle in E. coli cultures by inhibition of tRNA charging.

Biochem/physiol Actions

Serine is involved in the one-carbon unit metabolism. It is associated with the biosynthesis of cysteine, ceramide, phosphatidylserine, purine and pyrimidine. In bacteria, it participates in tryptophan synthesis. Gluconeogenesis, one of the important biochemical processes, involves serine, particularly in ruminants. Protein phosphorylation is one such event that utilizes serine. Glycine, a metabolic product of serine, serves as an antioxidant and a neurotransmitter. D-serine is known to activate the N-methyl-D-aspartate (NMDA) receptors of the brain. Serine hydroxamate, a structural analogue of serine prevents seryl-tRNA (transfer ribonucleic acid) charging and thereby decreases phospholipid and nucleic acid synthesis in Escherichia coli.

아미노산히드록사메이트DL-세린히드록사메이트 준비 용품 및 원자재

원자재

준비 용품


아미노산히드록사메이트DL-세린히드록사메이트 공급 업체

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Sigma-Aldrich 021-61415566 800-8193336
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