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WUWEIZISU C

WUWEIZISU C 구조식 이미지
카스 번호:
61301-33-5
상품명:
WUWEIZISU C
동의어(영문):
WUWEIZISU C;,8-dimethyl-;SCHIZANDRIN C;(S)-(-)-Schisandrin C;WUWEIZISU C USP/EP/BP;Schisandrin C >=98% (HPLC);Schisandrin C (Schizandrin-C;Schisandrin C (S)-(-)-Schisandrin C;13,14-dimethoxy-6,7-dimethyl-5,6,7,8-tetrahydro[1,3]benzodio...;cycloocta(1,2-f:3,4-f’)bis(1,3)benzodioxole6,7,8,9-tetrahydro-1,13-dimethoxy-7
CBNumber:
CB2327435
분자식:
C22H24O6
포뮬러 무게:
384.42
MOL 파일:
61301-33-5.mol
MSDS 파일:
SDS

WUWEIZISU C 속성

녹는점
122-123℃
끓는 점
549.2±50.0 °C(Predicted)
밀도
1.232
용해도
DMSO : 8.33 mg/mL (21.67 mM; Need ultrasonic)H2O : < 0.1 mg/mL (insoluble)
물리적 상태
가루
색상
하얀색
LogP
5.623 (est)
안전
  • 위험 및 안전 성명
  • 위험 및 사전주의 사항 (GHS)
그림문자(GHS): GHS hazard pictogramsGHS hazard pictograms
신호 어: Warning
유해·위험 문구:
암호 유해·위험 문구 위험 등급 범주 신호 어 그림 문자 P- 코드
H302 삼키면 유해함 급성 독성 물질 - 경구 구분 4 경고 GHS hazard pictograms P264, P270, P301+P312, P330, P501
H410 장기적 영향에 의해 수생생물에 매우 유독함 수생 환경유해성 물질 - 만성 구분 1 경고 GHS hazard pictograms P273, P391, P501
예방조치문구:
P264 취급 후에는 손을 철저히 씻으시오.
P264 취급 후에는 손을 철저히 씻으시오.
P270 이 제품을 사용할 때에는 먹거나, 마시거나 흡연하지 마시오.
P273 환경으로 배출하지 마시오.
P301+P312 삼켜서 불편함을 느끼면 의료기관(의사)의 진찰을 받으시오.
P330 입을 씻어내시오.
P391 누출물을 모으시오.
P501 ...에 내용물 / 용기를 폐기 하시오.
NFPA 704
0
2 0

WUWEIZISU C C화학적 특성, 용도, 생산

개요

Schisandrin C is a lignan originally isolated from Schizandrae that has diverse biological activities. It decreases viability of U937 cells in a concentration-dependent manner and induces cell cycle arrest at the G1 phase when used at a concentration of 100 μM. Schisandrin C (5-20 μM) decreases hydrogen peroxide-induced cell death and production of reactive oxygen species (ROS) in C2C12 skeletal muscle cells. It also decreases levels of matrix metalloproteinase-2 (MMP-2), MMP-9, COX-2, VCAM-1, IL-1β, and TNF-α in hydrogen peroxide-stimulated C2C12 cells. Schisandrin C decreases lipoteichoic acid-induced production of nitric oxide (NO), prostaglandin E2 (PGE2; ), TNF-α, IL-1β, and IL-6 in mouse primary microglia. In vivo, schisandrin C (200 mg/kg) decreases serum alanine amino transferase (ALT) and aspartate amino transferase (AST) activity, increases hepatic mitochondrial and total glutathione (GSH) levels, and reduces liver injury in a mouse model of acetaminophen-induced liver injury partially via inhibition of the cytochrome P450 (CYP) isoforms CYP2E1, CYP1A2, and CYP3A11.

용도

Schisandrin C potently inhibits proprotein convertase subtillsin-kexin type 9 (PCSK9) mRNA expression. Also, it displays strong protective effects in SH-SY5Y cells against serum and glucose deprivation (SGD) injury.

WUWEIZISU C 준비 용품 및 원자재

원자재

준비 용품

WUWEIZISU C 공급 업체

글로벌( 181)공급 업체
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Nanjing Dolon Biotechnology Co.,Ltd. 		18905173768
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Wuhan ChemNorm Biotech Co.,Ltd. 		+86-27-8439 4403 18971486879
 sales@chemnorm.com CHINA 2935 58

WUWEIZISU C 관련 검색:

4-4'-다이하이드록시디페닐 Schisantherin A Schisandrin schisanhenol WUWEIZISU B,WUWEIZISU B 98.0% BY HPLC WUWEIZISU A (5S)-6α,7β-Dimethyl-1,2,3,11,12-pentamethoxy(5,6,7,8-tetrahydrodibenzo[a,c]cyclooctene)-5α,6β,10-triol 5-benzoate Gomisin A 2-BUTENOIC ACID, 2-METHYL-, (5S,6S,7S,13AS)-5,6,7,13A-TETRAHYDRO-6-HYDROXY-1,2,3,13-TETRAMETHOXY-6,7-DIMETHYLBENZO[3,4]CYCLOOCTA[1,2-F][1,3]BENZODIOXOL-5-YL ESTER, (2Z)- Arisantetralone C 3,5,6,6-tetraMethyl-4,5,5a,6,7,8-hexahydrocyclopenta[c]pentalen-2(1H)-one schisantherin D SchisandraeChinensis polysaccharides Benzo(3,4)cycloocta(1,2-f)(1,3)benzodioxol-1-ol, 5,6,7,8-tetrahydro-2, 3,13-trimethoxy-6,7-dimethyl-, stereoisomer 4-HYDROXY-4'-METHOXYBIPHENYL 4,4'-Dimethoxybiphenyl Masoprocol 2,2'-DIMETHOXYBIPHENYL
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