ODVWZAKKCNHATB-UHFFFAOYSA-N

ODVWZAKKCNHATB-UHFFFAOYSA-N 구조식 이미지
카스 번호:
2108899-91-6
상품명:
ODVWZAKKCNHATB-UHFFFAOYSA-N
동의어(영문):
ODVWZAKKCNHATB-UHFFFAOYSA-N;CPTH2 (hydrochloride) (357649-93-5 free base);2-[4-(4-chlorophenyl)-2-thiazolyl]hydrazone-cyclopentanone,monohydrochloride
CBNumber:
CB23402948
분자식:
C14H15Cl2N3S
포뮬러 무게:
328.26
MOL 파일:
2108899-91-6.mol

ODVWZAKKCNHATB-UHFFFAOYSA-N 속성

용해도
DMF: 5 mg/ml; DMSO: 16 mg/ml; DMSO:PBS(pH 7.2) (1:2): 0.30 mg/ml; Ethanol: 5 mg/ml
물리적 상태
결정성 고체

안전

ODVWZAKKCNHATB-UHFFFAOYSA-N C화학적 특성, 용도, 생산

개요

Gcn5 is a chromatin modifying factor whose HAT activity is required to acetylate histone H3 lysine 9 (K9) and K14, which facilitates transcription elongation by relaxing nucleosomes. CPTH2 inhibits the HAT activity of Gcn5 both in vitro and in vivo, reducing histone H3K14 acetylation at a concentration of 0.8 mM. It is a useful tool to study the impact of Gcn5-dependent acetylation in various biological systems and recently has been used to control the replication of human adenovirus.

ODVWZAKKCNHATB-UHFFFAOYSA-N 준비 용품 및 원자재

원자재

준비 용품


ODVWZAKKCNHATB-UHFFFAOYSA-N 공급 업체

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