2-Phenylacetamide
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2-Phenylacetamide 속성
- 녹는점
- 156 °C
- 끓는 점
- 280-290 °C (dec.)
- 밀도
- 1.1031 (rough estimate)
- 굴절률
- 1.5589 (estimate)
- 저장 조건
- Refrigerator
- 용해도
- 메탄올에 용해됩니다.
- 산도 계수 (pKa)
- 16.21±0.40(Predicted)
- 물리적 상태
- 고체
- 물리적 상태
- 단단한 모양
- 색상
- 디스크 모양 또는 벗겨지기 쉬운 결정
- Merck
- 14,7266
- InChI
- InChI=1S/C8H9NO/c9-8(10)6-7-4-2-1-3-5-7/h1-5H,6H2,(H2,9,10)
- InChIKey
- LSBDFXRDZJMBSC-UHFFFAOYSA-N
- SMILES
- C1(CC(N)=O)=CC=CC=C1
- CAS 데이터베이스
- 103-81-1(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
| 위험품 표기 | Xi | ||
|---|---|---|---|
| 위험 카페고리 넘버 | 22-36 | ||
| 안전지침서 | 22-24/25-60-36-26 | ||
| RTECS 번호 | AC7705000 | ||
| TSCA | Yes | ||
| 위험 등급 | IRRITANT | ||
| HS 번호 | 29242990 | ||
| 독성 | LD50 ipr-mus: 430 mg/kg PCJOAU 10,579,76 |
2-Phenylacetamide C화학적 특성, 용도, 생산
화학적 성질
2-Phenylacetamide, also known as alpha-toluamide or benzeneacetamide, belongs to the class of organic compounds known as phenylacetamides. These are amide derivatives of phenylacetic acids. Pure crystals are plate shaped and colorless to white. soluble in hot water, ethanol, slightly soluble in cold water, ether and benzene.용도
In agriculture, 2-Phenylacetamid can be used in the production of many important intermediates of pesticides, such as carbamine. In the field of dyes: it can react with some monomers with color to produce some important raw materials for blue and purple dyes. In the field of fragrances, it can be used as an important raw material for the synthesis of certain spices and flavors. 2-Phenylacetamide can also be used in the synthesis of organometallic, organic peroxide, organic peroxide ester, and other compounds, and can be used as a crosslinking agent for polymers, a film forming agent for coatings, a plasticizer for plastics, etc.용도
2-Phenylacetamide is used as a pharmaceutical intermediate in the production of penicillin G and phenobarbital, etc. It is also used in organic synthesis.제조 방법
Synthesis of 2-phenylacetamide: Add concentrated hydrochloric acid to phenylacetonitrile, stir to dissolve, and react at 50°C for half an hour. Then slowly add water under cooling to separate out crystals, filter after cooling, wash with ice water to obtain crude product. The crude product was washed with sodium carbonate solution, then washed with ice water, and dried to obtain purer phenylacetamide.정의
ChEBI: 2-phenylacetamide is a monocarboxylic acid amide that is acetamide substituted by a phenyl group at position 2. It has a role as a mouse metabolite. It derives from a phenylacetic acid.Safety Profile
Moderately toxic by intraperitoneal route. When heated to decomposition it emits toxic fumes of NOx.Purification Methods
Crystallise the acetamide repeatedly from absolute EtOH, EtOAc (m 160-161o) or H2O (m 159-160o). Dry it in vacuo over P2O5. [Beilstein 9 H 347, 9 III 2193, 9 IV 1632.]2-Phenylacetamide 준비 용품 및 원자재
원자재
Concentrated hydrochloric acid
DimethylamineE
염화벤질
AMMONIUM POLYSULFIDE
페닐아세토나이트릴
Activated carbon,decolor
페닐초산
준비 용품
2-Phenylacetamide 공급 업체
글로벌( 417)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| Wuhan Aoliqisi New Material Technology Co., Ltd. | +86-13545906766; +8613545906766 |
sales@whaop.com | China | 263 | 58 |
| Hebei Weibang Biotechnology Co., Ltd | +8615350571055 |
Sibel@weibangbio.com | China | 6087 | 58 |
| CD Chemical Group Limited | +8615986615575 |
info@codchem.com | China | 20342 | 58 |
| Hebei Yanxi Chemical Co., Ltd. | +8617531190177 |
peter@yan-xi.com | China | 5858 | 58 |
| Hebei Weibang Biotechnology Co., Ltd | +8617732866630 |
bess@weibangbio.com | China | 18194 | 58 |
| Shijiazhuang Jianxin Biotechnology Co., LTD | +undefined-86-1906231316-9 +undefined86-19062313169 |
liyingjian1997@gmail.com | China | 709 | 58 |
| HebeiShuoshengImportandExportco.,Ltd | +86-18532138899 +86-18532138899 |
L18532138899@163.com | China | 939 | 58 |
| Hebei Mojin Biotechnology Co., Ltd | +86 13288715578 +8613288715578 |
sales@hbmojin.com | China | 12837 | 58 |
| Hebei Mojin Biotechnology Co.,Ltd | +86-15028179902 |
angelia@hbmojin.com | China | 1179 | 58 |
| Hebei Chuanghai Biotechnology Co,.LTD | +86-13131129325 |
sales1@chuanghaibio.com | China | 5893 | 58 |