ANTI-CHROMOBOX PROTEIN HOMOLOG 1
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ANTI-CHROMOBOX PROTEIN HOMOLOG 1 속성
- 저장 조건
- −20°C
- 물리적 상태
- 완충 수용액
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
| WGK 독일 | 3 |
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| 그림문자(GHS): |
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| 신호 어: | Warning | |||||||||||||||||||||
| 유해·위험 문구: |
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| 예방조치문구: |
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ANTI-CHROMOBOX PROTEIN HOMOLOG 1 C화학적 특성, 용도, 생산
일반 설명
The protein encoded by this gene (p35) is a neuron-specific activator of cyclin-dependent kinase 5 (CDK5); the activation of CDK5 is required for proper development of the central nervous system. The p35 form of this protein is proteolytically cleaved by calpain, generating a p25 form. The cleavage of p35 into p25 results in relocalization of the protein from the cell periphery to nuclear and perinuclear regions. P25 deregulates CDK5 activity by prolonging its activation and changing its cellular location. The p25 form accumulates in the brain neurons of patients with Alzheimer′s disease. This accumulation correlates with an increase in CDK5 kinase activity, and may lead to aberrantly phosphorylated forms of the microtubule-associated protein tau, which contributes to Alzheimer′s disease. (provided by RefSeq)ANTI-CHROMOBOX PROTEIN HOMOLOG 1 준비 용품 및 원자재
원자재
준비 용품
ANTI-CHROMOBOX PROTEIN HOMOLOG 1 공급 업체
글로벌( 9)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| Suzhou Ruinuode Biotechnology Co., Ltd. | -- |
2090855807@qq.com | CHINA | 6063 | 58 |
| Beijing Dakco is Biotechnology Co., Ltd. | -- |
bj_info@dakewe.net | CHINA | 6348 | 58 |
| Shanghai Yubo Biotechnology Co., Ltd. | -- |
shybio@126.com | CHINA | 6969 | 58 |
| Shanghai Zeye Biotechnology Co., Ltd. | -- |
shzeysw@163.com | CHINA | 6550 | 58 |
| Nanjing Sai Ruirui Biotechnology Co., Ltd. | -- |
sales@shrbio.com | CHINA | 6873 | 58 |
| Shanghai Beinuo Biotechnology Co., Ltd. | -- |
beinuobio@163.com | CHINA | 6580 | 58 |
| Riedel-de Haen AG | -- |
United States | 6825 | 87 | |
| SIGMA-RBI | -- |
Switzerland | 6913 | 91 | |
| Bethyl Laboratories, Inc. | -- |
bethyl@bethyl.com | United States | 679 | 75 |