Diosmetin
|
|
Diosmetin 속성
- 녹는점
- 256-258°C
- 끓는 점
- 576.7±50.0 °C(Predicted)
- 밀도
- 1.512±0.06 g/cm3(Predicted)
- 증기압
- 0Pa at 20℃
- 저장 조건
- Sealed in dry,2-8°C
- 용해도
- 아세토니트릴, DMSO(60mg/ml) 및 에탄올(17mg/ml)에 용해되며 투명하고 연한 노란색에서 노란색까지입니다.
- 물리적 상태
- Solid
- 산도 계수 (pKa)
- 6.50±0.40(Predicted)
- 색상
- 밝은 노란색에서 노란색까지
- 수용성
- 19μg/L at 20℃
- BRN
- 294492
- 안정성
- 흡습성
- InChIKey
- MBNGWHIJMBWFHU-UHFFFAOYSA-N
- LogP
- 3.1 at 20℃
- CAS 데이터베이스
- 520-34-3(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
위험품 표기 | Xi,Xn | ||
---|---|---|---|
위험 카페고리 넘버 | 22 | ||
안전지침서 | 24/25 | ||
WGK 독일 | 3 | ||
HS 번호 | 29329990 | ||
유해 물질 데이터 | 520-34-3(Hazardous Substances Data) | ||
기존화학 물질 | KE-10834 |
그림문자(GHS): | |||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
신호 어: | Warning | ||||||||||||||
유해·위험 문구: |
|
||||||||||||||
예방조치문구: |
|
Diosmetin C화학적 특성, 용도, 생산
화학적 성질
Diosmetin is a flavonoid compound that appears as a yellow powder. It is extracted from lemon and also found in various other natural plants, including spearmint and spider incense. Diosmetin is slightly soluble in methanol but readily dissolves in DMSO.용도
Diosmetin (Diosmin EP Impurity F) is a metabolite of Apigenin. It exhibits anticancer, antimicrobial, antioxidant, oestrogenic, and anti-inflamatory activities. Diosmetin can be used in the production of functional foods, cosmetics, and future drugs with antioxidant, anti-infective and anti-shock effects.정의
ChEBI: Diosmetin is a monomethoxyflavone that is the 4'-methyl ether derivative of luteolin. It is a natural product isolated from citrus fruits which exhibits a range of pharmacological activities. It has a role as an antioxidant, an antineoplastic agent, a plant metabolite, a tropomyosin-related kinase B receptor agonist, an apoptosis inducer, an angiogenesis inhibitor, a cardioprotective agent, a bone density conservation agent, an anti-inflammatory agent and a vasodilator agent. It is a monomethoxyflavone, a trihydroxyflavone and a 3'-hydroxyflavonoid. It is functionally related to a luteolin. It is a conjugate acid of a diosmetin-7-olate.참고 문헌
[1]. ciolino hp, wang tt and yeh gc. diosmin and diosmetin are agonists of the aryl hydrocarbon receptor that differentially affect cytochrome p450 1a1 activity. cancer res, 1998, 58(13):2754-60. PMID: 9661887[2]. gonzalez fj and fernandez-salguero p. the aryl hydrocarbon rreceptor studies using the ahr-null mice. drug metabolism and disposition, 1998, 26(12): 1194-1198. PMID: 9860927
[3]. and routsopoulos vp and spandidos da. The flavonoids diosmetin and luteolin exert synergistic cytostatic effects in human hepatoma HepG2 cells via CYP1A-catalyzed metabolism, activation of JNK and ERK and P53/P21 up-regulation. j nutr biochem, 2013, 24(2):496-504. DOI:10.1016/j.jnutbio.2012.01.012
Diosmetin 준비 용품 및 원자재
원자재
준비 용품
Diosmetin 공급 업체
글로벌( 348)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
---|---|---|---|---|---|
Changsha Staherb Natural Ingredients Co., Ltd. | +86-0731-84213302 +8618374838656 |
sales@staherb.cn | China | 1025 | 58 |
Hebei baicao biology science and technology co., ltd | +86-19131911055 +8617824879454 |
zhang@hbbocao.com | China | 1035 | 58 |
Hebei Kingfiner Technology Development Co.Ltd | +86-15532196582 +86-15373005021 |
lisa@kingfinertech.com | China | 2989 | 58 |
BINBO BIOLOGICAL CO.,LTD | +8618629063126 |
info@binbobiological.com | China | 346 | 58 |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 |
info@tianfuchem.com | China | 21673 | 55 |
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 |
ivan@atkchemical.com | China | 32760 | 60 |
Shanghai Zheyan Biotech Co., Ltd. | 18017610038 |
zheyansh@163.com | CHINA | 3620 | 58 |
career henan chemical co | +86-0371-86658258 +8613203830695 |
sales@coreychem.com | China | 29897 | 58 |
Chengdu Biopurify Phytochemicals Ltd. | +8618080483897 |
sales@biopurify.com | China | 3424 | 58 |
Nanjing Dolon Biotechnology Co.,Ltd. | 18905173768 |
sales@dolonchem.com | CHINA | 2972 | 58 |
Diosmetin 관련 검색:
루테올린 디오스민 시넨세틴
Eurycoma longifolia powder extract
Coumarin 6
Coumarin-3-carboxylic acid
BETA-RHODINOL
Coumarin 153
Diosmetin 7-O-β-D-glucopyranoside,Diosmetin 7-O-glucoside
3',4',5,7-TETRAMETHOXYFLAVONE
Diosmetin
TAMARIXETIN
QUERCETIN-3,7,3',4'-TETRAMETHYL ETHER
5,7-DIHYDROXY-3',4',5'-TRIMETHOXYFLAVONE
EUPATORIN-5-METHYL ETHER
3,7,3',4'-TETRAMETHYLGOSSYPETIN
3',5-DIHYDROXY-4',6,7-TRIMETHOXYFLAVONE
LUTEOLIN-4'-O-GLUCOSIDE