3-아미노-1H-피라졸로[3,4-B]퀴녹살린
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![3-아미노-1H-피라졸로[3,4-B]퀴녹살린](CAS/GIF/40254-90-8.gif)
3-아미노-1H-피라졸로[3,4-B]퀴녹살린 속성
- 녹는점
- 292-293℃ (ethanol )
- 끓는 점
- 522.8±45.0 °C(Predicted)
- 밀도
- 1.570±0.06 g/cm3(Predicted)
- 저장 조건
- Store at +4°C
- 용해도
- Soluble to 100 mM in DMSO
- 물리적 상태
- 빨간색 고체
- 산도 계수 (pKa)
- 7.40±0.50(Predicted)
- 색상
- Orange to red
안전
| 위험품 표기 | T | ||
|---|---|---|---|
| 위험 카페고리 넘버 | 25 | ||
| 안전지침서 | 45 | ||
| 유엔번호(UN No.) | UN 2811 6.1 / PGIII |
3-아미노-1H-피라졸로[3,4-B]퀴녹살린 C화학적 특성, 용도, 생산
개요
Cyclin-dependent kinases (Cdks) are key regulators of cell cycle progression and are therefore promising targets for cancer therapy. Cdk1/5 Inhibitor is a pyrazolo [3,4-b] quioxaline that inhibits Cdk1/cyclin B and Cdk5/p25 (IC50s = 600 and 400 nM, respectively). It less potently inhibits GSK3β (IC50 = 1 μM) and does not block Cdc25 activity. This compound is used to help define the roles of Cdk1 and Cdk5 in various signaling pathways.용도
Cyclin-dependent kinases (CDKs) are protein kinases and involved with the regulation of the cell cycle. NSC 693868 is an inhibitor of Cdk1/cyclin B and Cdk5/p25.?Small molecules that target these protein kinases are valuable tools for investigating cellular signaling pathways and are potential therapeutic agents.생물학적 활성
Inhibitor of cyclin-dependent kinases (cdks) and glycogen synthase kinase-3 (GSK-3). IC 50 values are 0.6, 0.4 and 1 μ M for cdk1/cyclin B, cdk5/p25 and GSK-3 respectively.3-아미노-1H-피라졸로[3,4-B]퀴녹살린 준비 용품 및 원자재
원자재
준비 용품
3-아미노-1H-피라졸로[3,4-B]퀴녹살린 공급 업체
글로벌( 52)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 |
marketing@targetmol.com | United States | 19892 | 58 |
| Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 |
sales@molcore.com | China | 49739 | 58 |
| ZHEJIANG JIUZHOU CHEM CO., LTD | +86-0576225566889 +86-13454675544 |
admin@jiuzhou-chem.com；jamie@jiuzhou-chem.com；alice@jiuzhou-chem.com | China | 19947 | 58 |
| Aladdin Scientific | +1-+1(833)-552-7181 |
sales@aladdinsci.com | United States | 52927 | 58 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 821-50328103-801 18930552037 |
3bsc@sina.com | China | 15848 | 69 |
| EMMX Biotechnology LLC | 888-539-0666 |
info@emmx.com | United States | 8449 | 60 |
| BOC Sciences | -- |
info@bocsci.com | USA | 0 | 65 |
| Jinan blalong chemical co. LTD | 2710913286@.com |
1513643261@qq.com | China | 14253 | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 |
sales@chemegen.com | China | 11289 | 58 |
| MedBioPharmaceutical Technology Inc | 021-69568360 18916172912 |
order@med-bio.cn | China | 8141 | 58 |