Hygroscopic, -20°C Freezer, Under inert atmosphere
용해도
메탄올(아주 소량), 물(미량, 초음파처리)에 용해됨
물리적 상태
고체
물리적 상태
단단한 모양
산도 계수 (pKa)
2.76±0.70(Predicted)
색상
흰색에서 연한 노란색
수용성
Water: slightly, sonicated
안전
Dolutegravir O-β-D-Glucuronide Impurity C화학적 특성, 용도, 생산
용도
Dolutegravir O-β-D-Glucuronide is a metabolite of Dolutegravir (D528800); a second generation HIV-1 integrase strand transfer inhibitor. Dolutegravir is currently in Phase III clinical trials for the treatment of HIV infection. Dolutegravir has been shown to potently inhibit HIV replication in cells such as peripheral blood mononuclear cells (PBMCs), MT-4 cells and CIP4 cells infected with a self-inactivating PHIV lentiviral vector.
Dolutegravir O-β-D-Glucuronide Impurity 준비 용품 및 원자재
