사이클릭피피트린-알파

사이클릭피피트린-알파
사이클릭피피트린-알파 구조식 이미지
카스 번호:
60477-34-1
한글명:
사이클릭피피트린-알파
동의어(한글):
사이클릭피피트린-알파
상품명:
CYCLIC-PIFITHRIN-ALPHA
동의어(영문):
Pifithrin-2;Pifithrin-alpha (cyclic) . HBr;Pifithrin-β (QB-102 and Cyclic-Pifithrin-α);Pifithrin-α, Cyclic- - CAS 60477-34-1 - Calbiochem;2-(p-Tolyl)-5,6,7,8-tetrahydrobenzo[d]imidazo[2,1-b]thiazole;5,6,7,8-Tetrahydro-2-(4-methylphenyl)-imidazo[2,1-b]benzothiazole;Imidazo[2,1-b]benzothiazole, 5,6,7,8-tetrahydro-2-(4-methylphenyl)-
CBNumber:
CB2504209
분자식:
C16H16N2S
포뮬러 무게:
268.38
MOL 파일:
60477-34-1.mol

사이클릭피피트린-알파 속성

녹는점
266.4-267.3 °C(lit.)
밀도
1.30±0.1 g/cm3(Predicted)
저장 조건
−20°C
용해도
DMSO: 20mg/mL
물리적 상태
흰색 고체
산도 계수 (pKa)
6.75±0.20(Predicted)

안전

WGK 독일 3

사이클릭피피트린-알파 C화학적 특성, 용도, 생산

일반 설명

A cell-permeable and very stable analog of Pifithrin-α (Cat. No. 506132), with similar biological function, but with reduced cytotoxicity. A chemical inhibitor of p53. Reversibly inhibits p53-dependent transactivation of p53-responsive genes; also reversibly blocks p53-mediated apoptosis. Acts as a P-gp modulator by changing relative substrate specificity of the transporter. This compound has been reported to be a potent STAT6 transcriptional inhibitor.

Biochem/physiol Actions

Cell permeable: yes

사이클릭피피트린-알파 준비 용품 및 원자재

원자재

준비 용품


사이클릭피피트린-알파 공급 업체

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ATK CHEMICAL COMPANY LIMITED
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InvivoChem
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Amadis Chemical Company Limited
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MedChemexpress LLC 021-58955995
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Shanghai Tauto Biotech Co., Ltd. 021-51320588
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Sigma-Aldrich 021-61415566 800-8193336
orderCN@merckgroup.com China 51471 80
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627
info@efebio.com China 9708 58

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