GW 766994

GW 766994 구조식 이미지
카스 번호:
408303-43-5
상품명:
GW 766994
동의어(영문):
GW 994;GW 766994;Benzamide, 4-[[[[[[(2S)-4-[(3,4-dichlorophenyl)methyl]-2-morpholinyl]methyl]amino]carbonyl]amino]methyl]-
CBNumber:
CB25419748
분자식:
C21H24Cl2N4O3
포뮬러 무게:
451.35
MOL 파일:
408303-43-5.mol

GW 766994 속성

끓는 점
685.8±55.0 °C(Predicted)
밀도
1.331±0.06 g/cm3(Predicted)
저장 조건
Store at -20°C
용해도
DMSO:56.0(Max Conc. mg/mL);124.07(Max Conc. mM)
물리적 상태
고체
산도 계수 (pKa)
13.40±0.46(Predicted)
색상
Light yellow to yellow

안전

GW 766994 C화학적 특성, 용도, 생산

개요

GW 766994 is an antagonist of chemokine (C-C motif) receptor 3 (CCR3) with a Ki value of 13.8 nM in an assay of eosinophil chemotaxis induced by chemokine (C-C motif) ligand 11 (CCL11). It decreases CCL11-induced cyclin-dependent kinase 5 (Cdk5) and tau phosphorylation and production of amyloid β (1-42) (Aβ42) in isolated mouse hippocampal neurons when used at a concentration of 10 μM.

GW 766994 준비 용품 및 원자재

원자재

준비 용품


GW 766994 공급 업체

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