락툴로오스
|
|
락툴로오스 속성
- 녹는점
- ~169 °C (dec.)
- 끓는 점
- 397.76°C (rough estimate)
- 알파
- -47 º (C=5, H2O, 12HR)
- 밀도
- 1,32g/cm
- 굴절률
- 1,45-1,47
- 저장 조건
- Refrigerator
- 용해도
- 물에 잘 녹고, 메탄올에 조금 녹고, 톨루엔에는 거의 녹지 않습니다.
- 물리적 상태
- 가루
- 산도 계수 (pKa)
- 11.67±0.20(Predicted)
- 색상
- 흰색에서 거의 흰색
- optical activity
- [α]20/D 48±2°, 24 hr, c = 1% in H2O
- 수용성
- 76.4G/100ML(30℃)
- Merck
- 5346
- BRN
- 93773
- BCS Class
- 2?
- InChIKey
- PFCRQPBOOFTZGQ-VZXVHDRGSA-N
- LogP
- -2.885 (est)
- CAS 데이터베이스
- 4618-18-2(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
| 안전지침서 | 24/25 | ||
|---|---|---|---|
| WGK 독일 | 2 | ||
| RTECS 번호 | LS6965000 | ||
| TSCA | Yes | ||
| HS 번호 | 29400090 | ||
| 기존화학 물질 | KE-17410 |
락툴로오스 C화학적 특성, 용도, 생산
화학적 성질
White Powder용도
Lactulose is is a synthetic, non-digestible sugar used in the treatment of chronic constipation; laxative.정의
ChEBI: A synthetic galactosylfructose disaccharide used in the treatment of constipation and hepatic encephalopathy.Indications
Osmotic laxatives (e.g., lactulose, sorbitol) are poorly absorbed or nonabsorbable compounds that draw additional fluid into the GI tract. Lumen osmolality increases, and fluid movement occurs secondary to osmotic pressure. Lactulose is a synthetic disaccharide that is poorly absorbed from the GI tract, since no mammalian enzyme is capable of hydrolyzing it to its monosaccharide components. It therefore reaches the colon unchanged and is metabolized by colonic bacteria to lactic acid and to small quantities of formic and acetic acids.Clinical Use
Lactulose is used in the treatment of hepatic encephalopathy.부작용
Since lactulose does contain galactose, it is contraindicated in patients who require a galactose-free diet. Metabolism of lactulose by intestinal bacteria may result in increased formation of intraluminal gas and abdominal distention.Purification Methods
Crystallise lactulose from MeOH or 50% MeOH. It mutarotates from [] D 20 -11.9o to –50.7o (c 1, H2O). [Montgomery & Hudson J Am Chem Soc 32 2101, 2104 1930, Beilstein 17 III/IV 3094, 17/7 V 214.] NMR in Me2SO at 24o shows 0% -pyranose, 27% -pyranose, 20% -furanose and 52% -furanose fforms [Angyal Adv Carbohydr Chem 42 15 1984].락툴로오스 준비 용품 및 원자재
원자재
beta-D-Fructopyranose
유당
D-GALACTOSE 1-[2-(2-AZIDOETHOXY)ETHOXYETHYL]-2,3,4,6-TETRA-O-ACETATE
알루미늄 소디움 옥사이드
D(-)-과당
준비 용품
락툴로오스 공급 업체
글로벌( 411)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| Hebei Guanlang Biotechnology Co,.LTD | +8619930503252 |
daisy@crovellbio.com | China | 5828 | 58 |
| Hebei Kingfiner Technology Development Co.Ltd | +86-15532196582 +86-15373005021 |
lisa@kingfinertech.com | China | 2989 | 58 |
| Hebei Jingbo New Material Technology Co., Ltd | +8619931165850 |
hbjbtech@163.com | China | 1000 | 58 |
| airuikechemical co., ltd. | +undefined86-15315557071 |
sales06@airuikechemical.com | China | 983 | 58 |
| Hebei Saisier Technology Co., LTD | +86-18400010335 +86-18034520335 |
admin@hbsaisier.cn | China | 996 | 58 |
| Hebei Longbang Technology Co., LTD | +86-18032476855 +86-18032476855 |
admin@hblongbang.com | China | 935 | 58 |
| HebeiShuoshengImportandExportco.,Ltd | +86-18532138899 +86-18532138899 |
L18532138899@163.com | China | 931 | 58 |
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 |
sales@capotchem.com | China | 29798 | 60 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 |
info@tianfuchem.com | China | 21668 | 55 |
| Shanxi Naipu Import and Export Co.,Ltd | +86-13734021967 +8613734021967 |
kaia@neputrading.com | China | 1011 | 58 |
락툴로오스 관련 검색:
D(-)-과당 디에틸스틸베스트롤 갈락토올리고사카라이즈 락툴로오스
D-GALACTOSE 1-[2-(2-AZIDOETHOXY)ETHOXYETHYL]-2,3,4,6-TETRA-O-ACETATE
TRIGALACTURONIC ACID
Senna leaf
Biofermine
beta-D-Fructopyranose
D-LACTULOSE OCTAACETATE
FRUCTOSE
LACTULOSE FOR SYSTEM SUITABILITY
[1-13CFRU]LACTULOSE
LACTULOSE, [D-GALACTOSE 6-3H]
A-LACTULOSE SYRUP,A-LACTULOSE
LACTULOSE,ALPHA-LACTULOSE
LACTULOSE EPL(CRM STANDARD)
LACTULOSE USP(CRM STANDARD)