L-161,982
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L-161,982 속성
- 밀도
- 1.37±0.1 g/cm3(Predicted)
- 저장 조건
- 2-8°C
- 용해도
- DMSO: 용해성15mg/mL, 투명
- 산도 계수 (pKa)
- 4.57±0.10(Predicted)
- 물리적 상태
- 가루
- 색상
- 흰색에서 베이지색
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
WGK 독일 | 3 |
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그림문자(GHS): |
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신호 어: | Warning | |||||||||||||||||||||||||||||||||||
유해·위험 문구: |
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예방조치문구: |
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L-161,982 C화학적 특성, 용도, 생산
개요
Prostaglandin E2 (PGE2) exerts its effects through four separate G coupled-용도
L-161,982 is an EP4 receptor antagonist, which blocks prostaglandin E2-induced signal transduction and cell proliferation in HCA-7 colon cancer cells.생물학적 활성
EP 4 receptor antagonist that is selective over all other members of the prostanoid receptor family (K i values are 0.024, 0.71, 1.90, 5.10, 5.63, 6.74, 19 and 23 μ M for human EP 4 , TP, EP 3 , DP, FP, IP, EP 1 and EP 2 receptors respectively). Suppresses PGE 2 -induced bone formation in rats and prevents the nociceptive response induced by misoprostol in formalin-injected mice.L-161,982 준비 용품 및 원자재
원자재
준비 용품
L-161,982 공급 업체
글로벌( 51)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
---|---|---|---|---|---|
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 |
marketing@targetmol.com | United States | 19892 | 58 |
Jilin Chinese Academy of Sciences-yanshen Technology | +undefined18143011203 |
info@chemextension.com | China | 42057 | 58 |
Aladdin Scientific | +1-+1(833)-552-7181 |
sales@aladdinsci.com | United States | 52927 | 58 |
3B Pharmachem (Wuhan) International Co.,Ltd. | 821-50328103-801 18930552037 |
3bsc@sina.com | China | 15848 | 69 |
Guangzhou Isun Pharmaceutical Co., Ltd | 020-39119399 18927568969 |
isunpharm@qq.com | China | 4428 | 55 |
Sigma-Aldrich | 021-61415566 800-8193336 |
orderCN@merckgroup.com | China | 51471 | 80 |
EMMX Biotechnology LLC | 888-539-0666 |
info@emmx.com | United States | 8449 | 60 |
Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 |
info@efebio.com | China | 9707 | 58 |
BOC Sciences | -- |
info@bocsci.com | USA | 0 | 65 |
DC Chemicals | 021-58447131 13564518121 |
sales@dcchemicals.com | China | 9412 | 58 |
L-161,982 관련 검색:
CJ-21058
GW 627368X
CJ-42794
Grapiprant
PROSTAGLANDIN F1ALPHA
Latanoprost
Misoprostol Acid
ONO-AE3-208
13,14-DIHYDROPROSTAGLANDIN E1
Prostaglandin F2a
PROSTAGLANDIN D2
6(R)-(4-CARBOXYPHENYLTHIO)-5(S)-HYDROXY-7(E),9(E),11(Z),14(Z)-EICOSATETRAENOIC ACID
11BETA-PROSTAGL AND IN F2ALPHA
LEUKOTRIENE B4 DIMETHYL AMIDE
LEUKOTRIENE D4
CJ 033466
L-161,982
4,5-DIETHYL-2,4-DIHYDRO 1,2,4-TRIAZOL-3 ONE