미크로노마이신
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미크로노마이신 속성
- 녹는점
- 260° (dec)
- 알파
- D20 +116° (c = 1 in water)
- 끓는 점
- 567.39°C (rough estimate)
- 밀도
- 1.2416 (rough estimate)
- 굴절률
- 1.7600 (estimate)
- 저장 조건
- 4°C, stored under nitrogen
- 물리적 상태
- Solid
- 산도 계수 (pKa)
- 13.29±0.70(Predicted)
- 색상
- Light yellow to yellow
- 수용성
- Water : 250 mg/mL (539.29 mM; Need ultrasonic)
안전
| 독성 | LD50 i.v. in mice: 93 mg/kg (Okachi) |
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미크로노마이신 C화학적 특성, 용도, 생산
개요
Micronomicin, formerly called sagamicin, was found in the culture broth of Micromonospora sagamiensis var. nonreducans by Kyowa Hakko Kogyo Company and Abbott Laboratories in 1974. The compound is identical with one of the minor components contained in gentamicin, gentamicin C2b, but it is produced as a single component. Its amino group at the 6 -position is methylated and is not subject to the enzymatic acetylation caused by resistant bacteria, including Pseudomonas aeruginosa. Micronomicin is less toxic than gentamicin to the renal and aural systems.용도
Gentamicin C2b (micronomicin) is a trisaccharide pentaaminoglycoside antibiotic belonging to the gentamicin class. Gentamicin C2b was isolated from Micromonospora sagamiensis var. nonreductans by researchers at Kyowa Hakko Kogyo in 1974. Gentamicin C2b has broad activity against Gram positive and Gram negative bacteria. More recently, gentamicin C2b has been shown to induce neuromuscular blockage.Antimicrobial activity
Antibacterial and pharmacokinetic properties are similar to those of its precursor gentamicin C1a but it is more resistant to AAC(6′). Dosage is similar to that for gentamicin, and should be controlled by blood level determinations. It is available in Japan.미크로노마이신 준비 용품 및 원자재
원자재
준비 용품
미크로노마이신 공급 업체
글로벌( 41)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| Standardpharm Co. Ltd. | 86-714-3992388 |
overseasales1@yongstandards.com | United States | 14332 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 |
marketing@targetmol.com | United States | 32165 | 58 |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 |
1026@dideu.com | China | 22783 | 58 |
| BOC Sciences | 16314854226; +16314854226 |
inquiry@bocsci.com | United States | 19741 | 58 |
| Shijiazhuang Ruitian Biochemical Co. Ltd | 0311-89102030 18031153398 |
3212842192@qq.com | China | 184 | 58 |
| Beijing HuaMeiHuLiBiological Chemical | 010-56205725 |
waley188@sohu.com | China | 12335 | 58 |
| ChemStrong Scientific Co.,Ltd | 0755-0755-66853366 13670046396 |
sales@chem-strong.com | China | 18042 | 56 |
| Lynnchem | 86-(0)29-85992781 17792393971 |
info@lynnchem.com | China | 4587 | 58 |
| Novachemistry | 44-20819178-90 02081917890 |
info@novachemistry.com | United Kingdom | 4381 | 58 |
| Shenzhen Polymeri Biochemical Technology Co., Ltd. | +86-400-002-6226 +86-13028896684; |
sales@rrkchem.com | China | 57412 | 58 |