DDIT3;GADD153;C/EBP-homologous protein;Recombinant Human GADD153;DNA-damage inducible transcript 3;Anti-CHOP, N-Terminal antibody produced in rabbit;Growth arrest and DNA-damage-inducible protein GADD153
Anti-CHOP, N-Terminal antibody has been used in protein extraction and western blotting.
일반 설명
CCAAT/enhancer-binding protein homologous protein (CHOP) is a transcriptional regulator, that is located on human chromosome 12q13. It is also known as DNA damage inducible transcript 3 (DDIT3).
Biochem/physiol Actions
CCAAT/enhancer-binding protein homologous protein (CHOP) controls endoplasmic reticulum (ER) stress-mediated apoptosis. It also modulates the transcription of cellular lipid metabolism. CHOP controls chronic kidney disease–induced vascular calcification.
