ANTI-LRP

ANTI-LRP C화학적 특성, 용도, 생산

용도

Anti-LRP1 (N-terminal) antibody produced in rabbit has been used in immunoblotting and immunofluorescence.

일반 설명

LDL receptor-related protein 1 (LRP1), also known as 2-macroglobulin receptor, is a large endocytic receptor, widely expressed on the surface and intracellular membranes of various cells. LRP1 is encoded by the gene mapped to human chromosome 12q13.3. The encoded protein is a member of the LDL receptor family. LRP1 is synthesized in the endoplasmic reticulum as a single-chain 600 kDa type I transmembrane glycosylated precursor that is cleaved subsequently in the Golgi complex into two subunits of 515 kDa and 85 kDa. The 515 kDa N-terminal subunit remains attached to the membrane through noncovalent association with the smaller 85 kDa C-terminal subunit, which contains the transmembrane and cytoplasmic domains.

Biochem/physiol Actions

LRP1 expression is essential for early embryonic development. LRP1 facilitates various biological processes including lipoprotein metabolism, proteinase regulation, lysosomal enzymes activation and entry of viruses and toxins into the cells. In addition, It also regulates cell signaling pathways, cell migration, and neurodevelopment. LRP1 has an ability to bind at least 30 different ligands such as lipoproteins, proteinases, proteinase-inhibitor complexes, extra cellular matrix (ECM) proteins and various intracellular proteins. It also binds to bacterial toxins and viruses.

ANTI-LRP 준비 용품 및 원자재

원자재

준비 용품

ANTI-LRP 공급 업체

공급자	전화	이메일	국가	제품 수	이점
Beijing Luyuan Bird Biotechnology Co., Ltd.	--	15810802415@139.com	CHINA	6757	58
Beijing Dongge Boye Biotechnology Co., Ltd.	--	1861586486@qq.com	CHINA	6652	58
Beijing Zhijie Fangyuan Technology Co., Ltd.	--	15810200961@163.com	CHINA	6984	58
Suzhou Ruinuode Biotechnology Co., Ltd.	--	2090855807@qq.com	CHINA	6063	58
Dongguan Biaobiao Experimental Equipment Technology Co., Ltd.	--		CHINA	6673	58
Beijing Huaxia Ocean Technology Co., Ltd.	--	huaxiabio@163.com	CHINA	6122	58
Nanjing Sai Ruirui Biotechnology Co., Ltd.	--	sales@shrbio.com	CHINA	6873	58
Beijing Bai Ao Si Biotechnology Co., Ltd.	--	yangmei@bioneeds.net	CHINA	6999	58
Beijing Xiangsheng Xingye Technology Co., Ltd.	--	xs_bio@163.com	CHINA	5130	58
Shanghai Ziqi Biological Technology Co., Ltd.	--	2453006496@qq.com	CHINA	6192	58