PD 117519

PD 117519 구조식 이미지
카스 번호:
96392-15-3
상품명:
PD 117519
동의어(영문):
CI 947;PD 11751;PD 117519;PD 117519,R;PD 117519 (CI947);N-[(R)-Indan-1-yl]adenosine;N-[(1R)-Indan-1-yl]adenosine;(R)-N-(2,3-Dihydro-1H-indenyl)adenosine;PD-117519;PD 117519;PD117519;CI 947;CI947;N-[(1R)-2,3-Dihydro-1H-inden-1-yl]adenosine
CBNumber:
CB31872452
분자식:
C19H21N5O4
포뮬러 무게:
383.4
MOL 파일:
96392-15-3.mol

PD 117519 속성

저장 조건
2-8°C
용해도
DMF: 10mg/mL; DMF:PBS (pH 7.2) (1:4): 0.2mg/mL; DMSO: 5mg/mL; Ethanol: 0.1mg/mL
물리적 상태
고체
색상
White to off-white
InChIKey
FSKMJUWPFLDDRS-BYMDKACISA-N
SMILES
OC[C@H]1O[C@@H](N2C3C(=C(N=CN=3)N[C@H]3C4=C(C=CC=C4)CC3)N=C2)[C@H](O)[C@@H]1O

안전

PD 117519 C화학적 특성, 용도, 생산

용도

N6-Substituted adenosine receptor agonist; a potential antihypertensive agent.

in vitro

PD 117519 (2-10 mg/kg; oral administration; 16-24 hours; male beagle dogs) treatment produces significant hemodynamic changes at Tmax (4 hours) follows by acute coronary vascular injury that is evident at 16 hours postdosing.Treatment with 2 or 10 mg/kg of PD 117519 produces significant increases in mean heart rate and decreases in mean indirectsystolic blood pressure at time of highest drug exposure, 4 hours postdosing.

PD 117519 준비 용품 및 원자재

원자재

준비 용품


PD 117519 공급 업체

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