Pegylated Recombinant Human Interferon alfa-2a

Pegylated Recombinant Human Interferon alfa-2a 구조식 이미지
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상품명:
Pegylated Recombinant Human Interferon alfa-2a
동의어(영문):
Pegylated Recombinant Human Interferon alfa-2a
CBNumber:
CB32131314
분자식:
포뮬러 무게:
0
MOL 파일:
Mol file

Pegylated Recombinant Human Interferon alfa-2a 속성

안전

Pegylated Recombinant Human Interferon alfa-2a C화학적 특성, 용도, 생산

일반 설명

Pegylated interferon alfa-2a, Pegasys, is a covalent conjugateof recombinant interferon alfa-2a (approximate molecularmass, 20 kDa) with a singly branched bis-monomethoxy PEGchain (approximate molecular mass, 40 kDa). The PEG moietyis linked at a single site to the interferon alfa moiety by astable amide bond to lysine. Peginterferon alfa-2a has anapproximate molecular mass of 60 kDa. Pegasys providessustained therapeutic serum levels for up to a full week(168 hours). The drug is approved for the treatment of adultswith chronic hepatitis C who have compensated liver diseaseand who have not been previously treated with interferon alfa.Efficacy has also been demonstrated in patients with compensatedcirrhosis.

Pegylated Recombinant Human Interferon alfa-2a 준비 용품 및 원자재

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