2-아미노-3-메틸-3H-이미다졸-4-카르복실산에틸에스테르

2-아미노-3-메틸-3H-이미다졸-4-카르복실산에틸에스테르 속성

2-아미노-3-메틸-3H-이미다졸-4-카르복실산에틸에스테르 C화학적 특성, 용도, 생산

Synthesis

A solution of N-formyl sarcosine ethyl ester in an equal mixture of ethyl formate and THF with cyclohexane was added slowly to NaH (60% wt in mineral oil) at RT. After that, the hydrogen release stopped, and the reaction mixture was unde-stirred for 3.5 h. The reaction mixture was concentrated under a vacuum and then suspended in a solution of EtOH containing concentrated aq.HCl 32%. After refluxing for 2 h, the hot reaction mixture was filtered and the resulting solid was washed with boiling EtOH. The filtrate was concentrated under vacuum and diluted with a mixture of EtOH/water. The pH was adjusted to 3, using an aqueous 5M solution of NaOH, and cyanamide was added. The resulting mixture was refluxed for 1.5 h, then cooled to rt and concentrated under reduced pressure to approximately 1/8 of the initial volume. The pH of the remaining solution was adjusted to 9-10 with a saturated aqueous solution of potassium carbonate, after cooling in an ice-water bath. The precipitate formed was removed by filtration, washed with water, and dried under vacuum at 40 °C overnight to afford Ethyl 2-amino-1-methyl-1H-imidazole-5-carboxylate as a pale yellow to orange solid.

2-아미노-3-메틸-3H-이미다졸-4-카르복실산에틸에스테르 준비 용품 및 원자재

원자재

준비 용품

2-아미노-3-메틸-3H-이미다졸-4-카르복실산에틸에스테르 공급 업체

공급자	전화	이메일	국가	제품 수	이점
Capot Chemical Co.,Ltd.	571-85586718 +8613336195806	sales@capotchem.com	China	29798	60
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32760	60
Shenzhen Nexconn Pharmatechs Ltd	+86-755-89396905 +86-15013857715	admin@nexconn.com	China	10312	58
Jinan Carbotang Biotech Co.,Ltd.	+8615866703830	figo.gao@foxmail.com	China	7513	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49391	58
career henan chemical co	+86-0371-86658258 +8613203830695	factory@coreychem.com	China	29825	58
Shanghai Gubang New Materail Technology Co. LTD	21-51317962 +8618721305404	16728589@qq.com	CHINA	272	58
Finetech Industry Limited	+86-27-87465837 +8618971612321	info@finetechnology-ind.com	China	9618	58
Baoji Guokang Healthchem co.,ltd	+8615604608665 15604608665	dominicguo@gk-bio.com	CHINA	9427	58
Hefei Hirisun Pharmatech Co., Ltd	+8615056975894	shawn@hirisunpharm.com	CHINA	9923	58

2-아미노-3-메틸-3H-이미다졸-4-카르복실산에틸에스테르 관련 검색: