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톨부타미드-d9

톨부타미드-d9 구조식 이미지

카스 번호:: 1219794-57-6

한글명:: 톨부타미드-d9

동의어(한글):: 톨부타미드-d9

상품명:: Tolbutamide-d9

동의어(영문):: Mobenol-d9;Artozin-d9;Artosin-d9;[2H9]-Tolbutamide;Tolylsulfonylbutylurea-d9;Tolbutamide-d9 Solution, 100ppm;3-(p-Tolyl-4-sulfonyl)-1-butylurea-d9;1-(Butyl-3-(p-tolyl- sulfonyl)urea-d9;N-Butyl-N'-(4-Methylphenylsulfonyl)urea-d9;N-[(ButylaMino-d9)carbonyl]-4-MethylbenzenesulfonaMide

CBNumber:: CB32512331

분자식:: C12H18N2O3S

포뮬러 무게:: 270.35

MOL 파일:: 1219794-57-6.mol

속성

안전

용도

공급 업체 19

톨부타미드-d9 속성

녹는점: 108-111°C

저장 조건: Refrigerator

용해도: DMF: 30 mg/ml,DMSO: 30 mg/ml,Ethanol: 30 mg/ml,Ethanol:PBS (pH 7.2) (1:1): 0.14 mg/ml

물리적 상태: 고체

색상: White to off-white

안전

위험 및 안전 성명

그림문자(GHS):

신호 어:

Warning

유해·위험 문구:

암호	유해·위험 문구	위험 등급	범주	신호 어	그림 문자	P- 코드

예방조치문구:

NFPA 704

	0
2		0

톨부타미드-d9 C화학적 특성, 용도, 생산

개요

Tolbutamide-d₉ is intended for use as an internal standard for the quantification of tolbutamide by GC- or LC-MS. Tolbutamide is an inhibitor of sulfonylurea receptor 1 (SUR1) linked to ATP-sensitive potassium channel K_ir6.2 (IC₅₀ = 4.9 μM). It is selective for SUR1/K_ir6.2 over SUR2A/K_ir6.2 and SUR2B/K_ir6.2 channels (IC₅₀s = 85 and 88 μM, respectively). Tolbutamide increases glucose-induced insulin secretion and calcium influx in isolated mouse pancreatic islets. In vivo, tolbutamide (80 mg/kg) reduces blood glucose levels in a mouse model of diabetes induced by streptozotocin (STZ; ). Formulations containing tolbutamide have been used in the treatment of type 2 diabetes.

화학적 성질

White Solid

용도

Labelled Tolbutamide (T535150). An antidiabetic, used as a hypoglycemic agent in veterinary medicine.

톨부타미드-d9 준비 용품 및 원자재

원자재

준비 용품

톨부타미드-d9 공급 업체

글로벌( 19)공급 업체

공급자	전화	이메일	국가	제품 수	이점
Hubei Jusheng Technology Co.,Ltd.	18871490254	linda@hubeijusheng.com	CHINA	28180	58
J & K SCIENTIFIC LTD.	010-82848833 400-666-7788	jkinfo@jkchemical.com	China	94717	76
Chemsky（shanghai）International Co.,Ltd.	021-50135380	shchemsky@sina.com	China	32344	50
Alta Scientific Co., Ltd.	022-6537-8550 15522853686	sales@altasci.com.cn	China	4515	55
Nanjing Haolv Biotechnology Co.,Ltd	025-84622273 02584622273;	kexin.zhou@haolvbiotech.com	China	3022	58
Shenzhen Polymeri Biochemical Technology Co., Ltd.	+86-400-002-6226 13028896684	sales@rrkchem.com	China	56057	58
Energy Chemical	021-58432009 400-005-6266	marketing1@energy-chemical.com	China	44843	58
ChengDu SinoStandards Bio-Tech Co.,Ltd. ，	028-83243028 19136088901	sinostandards@163.com	China	5359	58
Yancheng Tongming Biotechnology Co., Ltd.	15195160625	2863565288@qq.com	China	5194	58
ChemeGen 中国	18818260767	sales@chemegen.com	China	6975	58

톨부타미드-d9 관련 검색:

TOLAZAMIDE Tolbutamide Impurity 5 4-Carboxytolbutamide Methyl Ester TOLBUTAMIDE Tolbutamide 4-Carboxy Ethyl Ester 4-Hydroxytolbutamide