Doxycycline monohydrate
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Doxycycline monohydrate 속성
- 녹는점
- 167-168℃
- 저장 조건
- Sealed in dry,Store in freezer, under -20°C
- 용해도
- DMSO: 용해성1mg/mL
- 물리적 상태
- 분말 또는 결정
- 색상
- 연노랑
- 수용성
- 에탄올이나 메탄올에 용해됩니다. 물에 거의 용해되지 않습니다. 묽은 산, 알칼리 수산화물 및 디메틸 설폭사이드에 용해됩니다.
- CAS 데이터베이스
- 17086-28-1
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
위험품 표기 | Xi,Xn | ||
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위험 카페고리 넘버 | 36/37/38-22-63 | ||
안전지침서 | 26-36/37 | ||
WGK 독일 | 3 | ||
HS 번호 | 29413000 |
그림문자(GHS): |
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신호 어: | Warning | ||||||||||||||
유해·위험 문구: |
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예방조치문구: |
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Doxycycline monohydrate C화학적 특성, 용도, 생산
개요
Doxycycline is a broad-spectrum antibiotic synthetically derived from oxytetracycline. It is a semi-synthetic tetracycline. Doxycycline penetrates the bacterial cell and interferes with the protein biosynthesis, stopping the process. Other microorganisms are also sensitive to the antibiotic activity of Doxycycline, such as Mycoplasma, Chlamydia and Ricketsiae. Resistance to antibiotics of the tetracycline family is primarily due to inhibition of transport of the drug into the cell or by increasing antibiotic efflux. The biological mechanism is mainly through plasmid mediation but it may also occur by chromossomal alteration.화학적 성질
Doxycycline monohydrate is a Yellow, crystalline powder. It is soluble in ethanol or methanol. It has a high degree of lipid solubility and a low affinity for calcium binding. It is highly stable in normal human serum. It is very slightly soluble in water.용도
Doxycycline Monohydrate is used to treat bacterial infections, Lyme disease, chlamydia, Rocky Mountain Spotted Fever, and other susceptible bacterial infections. It is an antibiotic with bacteriostatic properties.Tetracycline antibacterial.
정의
ChEBI: The monohydrate form of doxycycline. A semi-synthetic tetracycline antibiotic, it is used to inhibit bacterial protein synthesis and treat non-gonococcal urethritis and cervicitis, exacerbations of bronchitis in patients with chronic obstructive pulmonary isease (COPD), and adult periodontitis.주요 응용
In yeast cells, doxycycline has been used in doxycycline-inducible system for overexpression of methyltransferase Hmt1 (hnRNP methyltransferase 1).It has been used in the doxycycline-inducible IFITM (interferon-induced transmembrane) cell lines.
It has also been used as an antimicrobial agent.
Indications
Doxycycline monohydrate (Vibramycin Monohydrate, Monodox, Mondoxyne NL) is a moderately priced drug used to treat many kinds of infections, like dental, skin, respiratory, and urinary tract infections. It also treats acne, Lyme disease, malaria, and certain sexually transmitted infections. This drug is more popular than comparable drugs. It is available in multiple brand and generic versions. Generic doxycycline monohydrate is covered by most Medicare and insurance plans, but some pharmacy coupons or cash prices may be lower. The lowest GoodRx price for the most common version of doxycycline monohydrate is around $6.02, 80% off the average retail price of $30.66. Compare tetracycline antibiotics.일반 설명
Doxycycline was synthesized by Pfizer starting with either tetracycline or oxytetracycline in 1958. It shows about fourfold higher antibacterial activity than tetracycline against a variety of pathogens. Doxycycline shows higher oral absorption than tetracycline, and its concentration in tissue is higher and maintained longer. Hyclate is a preparation of doxycycline containing one mole of hydrochloric acid and one-half mole each of ethanol and water per mole of doxycycline.생물학적 활성
Doxycycline is a semisynthetic tetracycline that is active against bacteria, mycoplasma and protozoan parasites. It inhibits the bacterial protein synthesis by inhibiting the interaction of aminoacyl-tRNA and the bacterial ribosome.Doxycycline monohydrate 준비 용품 및 원자재
원자재
준비 용품
Doxycycline monohydrate 공급 업체
글로벌( 225)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
---|---|---|---|---|---|
Zibo Hangyu Biotechnology Development Co., Ltd | +86-0533-2185556 +8617865335152 |
Mandy@hangyubiotech.com | China | 10978 | 58 |
Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 |
sales@capotchem.com | China | 29798 | 60 |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 |
info@tianfuchem.com | China | 21673 | 55 |
Hubei Jusheng Technology Co.,Ltd. | 18871490254 |
linda@hubeijusheng.com | CHINA | 28180 | 58 |
Xiamen AmoyChem Co., Ltd | +86-592-6051114 +8618959220845 |
sales@amoychem.com | China | 6387 | 58 |
Hubei xin bonus chemical co. LTD | 86-13657291602 |
linda@hubeijusheng.com | CHINA | 22968 | 58 |
Changzhou Carman Chemical Co., Ltd. | 15061933924 |
CHINA | 514 | 58 | |
Alchem Pharmtech,Inc. | 8485655694 |
sales@alchempharmtech.com | United States | 63711 | 58 |
Neostar United (Changzhou) Industrial Co., Ltd. | +86-519-519-85557386 |
marketing1@neostarunited.com | China | 12126 | 58 |
SIMAGCHEM CORP | +86-13806087780 |
sale@simagchem.com | China | 17367 | 58 |
Doxycycline monohydrate 관련 검색:
독시시크린 히클라산염 3-(디메틸아미노)프로필아민 P-다이메틸아미노벤즈알데하이드 4-다이메틸아미노피리딘 2-디메틸아미노에탄올 나프타센 염산 옥시테트라사이클린
MELIBIOSE
Doxycycline
Doxycycline Impurity 7(N-Desmethyl Doxycycline)
Doxycycline Hyclate IMpurity F
METHACYCLINE
Oxytetracycline
epi-Doxycycline
6-Deoxy-4-epioxytetracycline
DOXYCYCLINE SSA
4-Epi-6-epi Doxycycline
Doxycycline Hydrate