ML 18
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ML 18 속성
- 끓는 점
- 821.8±65.0 °C(Predicted)
- 밀도
- 1.291±0.06 g/cm3(Predicted)
- 저장 조건
- 2-8°C
- 용해도
- DMSO: 용해될 수 있다
- 물리적 상태
- 고체
- 산도 계수 (pKa)
- 11.99±0.46(Predicted)
- 색상
- White to yellow
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
ML 18 C화학적 특성, 용도, 생산
개요
ML-18 is a non-peptide bombesin receptor subtype 3 (BB3) antagonist that inhibits [125I]BA1 binding to NCI-H1299 lung cancer cells transfected with human BB3 receptors (IC50 = 4.8 μM). It is selective for BB3 over the gastrin releasing peptide receptor (GRPR) and the neuromedin B receptor (NMBR) with IC50 values of 16 and >100 μM, respectively, in a radioligand binding assay. ML-18 (16 μM) reversibly inhibits BA1-induced increases in cytosolic calcium in NCI-H1299 cells. It also inhibits BA1-induced phosphorylation of ERK and EGFR and reduces proliferation of NCI-H1299 cells.용도
ML-18 is a non-peptide bombesin receptor subtype-3 antagonist. It also inhibits lung cancer growth.ML 18 준비 용품 및 원자재
원자재
준비 용품
ML 18 공급 업체
글로벌( 47)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
---|---|---|---|---|---|
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 |
ivan@atkchemical.com | China | 32957 | 60 |
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 |
marketing@targetmol.com | United States | 32165 | 58 |
InvivoChem | +1-708-310-1919 +1-13798911105 |
sales@invivochem.cn | United States | 6391 | 58 |
TargetMol Chemicals Inc. | |
support@targetmol.com | United States | 38632 | 58 |
ShenZhen Trendseen Biological Technology Co.,Ltd. | 13417589054 |
trendseenbio@gmail.com | China | 11681 | 58 |
Wuhan Topule Biopharmaceutical Co., Ltd | +8618327326525 |
masar@topule.com | China | 8467 | 58 |
Aladdin Scientific | +1-+1(833)-552-7181 |
sales@aladdinsci.com | United States | 57505 | 58 |
Shanghai JiYi Biotechnology Co. Ltd. | 13621943973 |
sales@shjiyipharmatech.com | China | 1166 | 55 |
Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 |
info@efebio.com | China | 9806 | 58 |
Shanghai Chaolan Chemical Technology Center | 021-QQ:65489617 15618227136 |
Sales@ATKchemical.com | China | 7268 | 58 |
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