IGM

IGM C화학적 특성, 용도, 생산

Clinical Use

IgM (Fc = μ) is present at a concentration ofabout 1.5 mg/mL and has a half-life of less than 1 week. ThisAb participates in opsonization, agglutination reactions, andcomplement fixation. Opsonization, as stated previously, is a“protein coating” or tagging of a bacterium that renders itmore susceptible to phagocytosis. A complex of the Fc portionof IgM plus C3b of complement is that protein. IgM isthe first immunoglobulin formed during immunization, but itwanes and gives way to IgG. IgM is a pentamer, and its agglutinationpotency is about 1,000 times that of IgG. IgM isalso responsible for the A, B, and O blood groups. The fundamentalmonomeric IgM structure is much like that of IgG.The pentamer is held together by disulfide bonds and a singleJ (joining) peptide. The affinity of an IgM monomer forantigen is less than that of IgG, but the multimeric structureraises the avidity of the molecule for an antigen.

IGM 준비 용품 및 원자재

원자재

준비 용품

IGM 공급 업체

공급자	전화	이메일	국가	제품 수	이점
Sigma-Aldrich	021-61415566 800-8193336	orderCN@merckgroup.com	China	51456	80
Shanghai Yaji Biological Technology Co., Ltd.	021-34661275 15301693058	yajikit@163.com	China	9747	58
Biolab Reagents	18108604356 18108604356	info@biolabreagent.com	China	9868	58
ZSGB-BIO	02-400-810-9781 400810978	sales@zsbio.com	China	2887	58
Bio Rad Laboratories Inc	65-64153170	Sales.China@bio-rad.com	China	10054	58
CalBioreagents Inc	91-66301475	info@calbioreagents.com	China	261	58
Signalway Antibody LLC	025-58868422	info@sabbiotech.com	China	99242	58