ChemicalBook >제품 카탈로그 >H-8이수소화물

H-8이수소화물

H-8이수소화물 구조식 이미지

카스 번호:: 113276-94-1

한글명:: H-8이수소화물

동의어(한글):: H-8이수소화물

상품명:: H-8 DIHYDROCHLORIDE

동의어(영문):: H-8;H-8 HYDROCHLORIDE;H-8 DIHYDROCHLORIDE;H-8 dihydrochloride,98%;H8, dihydrochloride salt;H-8 dihydrochloride >98% (HPLC);H8 (hydrochloride),H 8 (hydrochloride);H-8 DIHYDROCHLORIDE POTENT INHIBITOR OF C;N-[2-(methylamino)ethyl]isoquinoline-5-sulfonamide;2-(5-isoquinolinylsulfonylamino)ethyl-methylammonium

CBNumber:: CB3341825

분자식:: C12H17Cl2N3O2S

포뮬러 무게:: 338.25

MOL 파일:: 113276-94-1.mol

MSDS 파일:: SDS

속성

안전

용도

공급 업체 75

H-8이수소화물 속성

녹는점: 221-222℃ (methanol water )

저장 조건: 2-8°C

용해도: 에탄올: 25 mg/mL, 투명, 무색

물리적 상태: 동결건조된

색상: 흰색에서 황백색까지

CAS 데이터베이스: 113276-94-1(CAS DataBase Reference)

안전

안전지침서	22-24/25
WGK 독일	3
HS 번호	29334990

H-8이수소화물 C화학적 특성, 용도, 생산

개요

The H series isoquinolinesulfonamide protein kinase (PK) inhibitors are widely used to block signaling pathways to elucidate mechanisms of cellular regulation and signal transduction. H-8, an isoquinolinesulfonamide protein kinase (PK) inhibitor, is a potent inhibitor of PKA and PKG and shows moderate inhibition for PKC and MLCK with K_i values of 1.2, 0.48, 15, and 68 μM, respectively. H-8 can disrupt transcriptional elongation by inhibiting cyclin C/Cdk8 and cyclin H/Cdk7/p36 CTD kinase activity with IC₅₀ values of 47 and 6.2 μM, respectively.

화학적 성질

white to off-white crystalline solid

용도

Active inhibitor of cyclic-nucleotide-dependent protein kinases.

H-8이수소화물 준비 용품 및 원자재

원자재

준비 용품

H-8이수소화물 공급 업체

글로벌( 75)공급 업체

공급자	전화	이메일	국가	제품 수	이점
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63711	58
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	19892	58
Career Henan Chemica Co	+86-0371-86658258 +8613203830695	laboratory@coreychem.com	China	30253	58
Aladdin Scientific	+1-+1(833)-552-7181	sales@aladdinsci.com	United States	52927	58
Amadis Chemical Company Limited	571-89925085	sales@amadischem.com	China	131980	58
Mainchem Co., Ltd.	+86-0592-6210733	sale@mainchem.com	China	32360	55
J & K SCIENTIFIC LTD.	010-82848833 400-666-7788	jkinfo@jkchemical.com	China	94717	76
Meryer (Shanghai) Chemical Technology Co., Ltd.	021-61259108 18621169085	market03@meryer.com	China	40240	62
3B Pharmachem (Wuhan) International Co.,Ltd.	821-50328103-801 18930552037	3bsc@sina.com	China	15848	69
Chemsky（shanghai）International Co.,Ltd.	021-50135380	shchemsky@sina.com	China	32344	50

H-8이수소화물 관련 검색:

염산 m-페닐렌 디아민 P-페닐렌디아민 디수화염화물 트리플루오페라진 디하이드로클로라이드 1,4-디아미노부탄-2,2,3,3-d4 디하이드로클로라이드 N-(2-[P-BROMOCINNAMYLAMINO]ETHYL)-5-ISOQUINOLINESULFONAMIDE HYDROCHLORIDE 1-(5-ISOQUINOLINESULFONYL)PIPERAZINE, DIHYDROCHLORIDE FASUDIL 1,4-BIS[3-(3,4,5-TRIMETHOXYBENZOYLOXY)PROPYL]HOMOPIPERAZINE DIHYDROCHLORIDE 1,4'-BIPIPERIDINE DIHYDROCHLORIDE,[1,4']BIPIPERIDINYL DIHYDROCHLORIDE 1-(3-TRIFLUOROMETHYL-PHENYL)-PIPERAZINE DIHYDROCHLORIDE 1-(4-Bromophenyl)piperazine 1,4-BUTANEDIAMINE DIHYDROCHLORIDE 1-(3-METHOXYPHENYL)PIPERAZINE DIHYDROCHLORIDE 1,3-PROPANEDIAMINE DIHYDROCHLORIDE 1-(3-METHYLPHENYL)PIPERAZINE DIHYDROCHLORIDE HYDRATE,1-(3-Methylphenyl)piperazine dihydrochloride [1,4']BIPIPERIDINYL DIHYDROCHLORIDE 1-(8-CHLORO-5-ISOQUINOLINESULFONYL)PIPERAZINE, DIHYDROCHLORIDE (S)-Isoquinoline-5-sulfonic acid pyrrolidin-3-ylamide dihydrochloride