Cucurbitacin E
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Cucurbitacin E 속성
- 녹는점
- 228-234°C
- 알파
- D -59° (c = 0.7 in chloroform)
- 끓는 점
- 545.56°C (rough estimate)
- 밀도
- 1.1059 (rough estimate)
- 굴절률
- 1.4900 (estimate)
- 저장 조건
- -20°C
- 용해도
- DMSO: 용해성15mg/mL, 투명
- 물리적 상태
- 가루
- 산도 계수 (pKa)
- 8.51±0.70(Predicted)
- 색상
- 흰색에서 베이지색
- optical activity
- [α]/D -60 to -75°, c = 0.7 (CDCl3)
- InChIKey
- NDYMQXYDSVBNLL-MUYMLXPFSA-N
- LogP
- 3.150 (est)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
| 위험품 표기 | Xn | ||
|---|---|---|---|
| 위험 카페고리 넘버 | 25-22 | ||
| 안전지침서 | 1-22-45-24/25 | ||
| 유엔번호(UN No.) | 3172 | ||
| WGK 독일 | 3 | ||
| RTECS 번호 | RC6305500 | ||
| HS 번호 | 29153900 | ||
| 독성 | LD50 orally in mice: 340 mg/kg (Albert) |
Cucurbitacin E C화학적 특성, 용도, 생산
개요
Cucurbitacin E is a plant-derived triterpene that has diverse biological activities. At a concentration of 10 pM, it reduces MPP+-induced death of neuronal PC12 cells through inhibition of autophagy in vitro. Cucurbitacin E inhibits growth of T24 bladder, MDA-MB-468 and MCF-7 breast, PC3 prostate, and colorectal cancer cell lines (IC50s = 50-1,000 nM) through induction of G2/M arrest and apoptosis. It increases bilirubin binding to human serum albumin (HSA) in human plasma in a dose-dependent manner. Cucurbitacin E also inhibits depolymerization of actin filaments isolated from rabbit skeletal muscle actin and in HeLa cells.화학적 성질
white to beige powder용도
Cucurbitacin E is a biochemical compound from the family of Cucurbitacins. Cucurbitacin E is a highly oxidated steroid consisting of a tetracyclic triterpene. Cucurbitacin E is known to possess broad spectrum of potential anti-inflammatory, antitumor andantioxidant effects.정의
ChEBI: A cucurbitacin in which a lanostane skeleton is multi-substituted with hydroxy, methyl and oxo substituents, with unsaturation at positions 1, 5 and 23.일반 설명
This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG.Cucurbitacin E 준비 용품 및 원자재
원자재
준비 용품
Cucurbitacin E 공급 업체
글로벌( 199)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| Shanghai Zheyan Biotech Co., Ltd. | 18017610038 |
zheyansh@163.com | CHINA | 3620 | 58 |
| Chengdu Greenpure Biopharma CO.,Ltd | +8618283602253 |
jancyzheng@gcgreenpure.com | China | 952 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 |
sales@coreychem.com | China | 29897 | 58 |
| Chengdu Biopurify Phytochemicals Ltd. | +8618080483897 |
sales@biopurify.com | China | 3424 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 |
linda@hubeijusheng.com | CHINA | 28180 | 58 |
| Shaanxi Pioneer Biotech Co., Ltd . | +8613259417953 |
sales@pioneerbiotech.com | China | 3000 | 58 |
| NanJing Spring & Autumn Biological Engineering CO., LTD. | +8613815430202 |
sale02@cqherb.com | CHINA | 376 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 |
sales@chemdad.com | China | 39916 | 58 |
| Shanghai Standard Technology Co., Ltd. | 18502101150 |
ft-sales@nature-standard.com | CHINA | 1923 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 |
sales@conier.com | China | 49391 | 58 |
Cucurbitacin E 관련 검색:
6,10,14-트라이메틸-2-펜타데카논 디메틸-5-헵텐-1알,테크 1,2-사이클로헥산디온
Cucurbitacin C
Cucurbitacin,CUCURBITACIN B(RG),CUCURBITACIN B
CUCURBITACIN D,CUCURBITACIN D WITH HPLC
ADOXAL
Calebassine
CUCURBITACIN D(SH)
Cucurbitacin IIb
CUCURBITACIN IIA
CUCURBITACIN I hplc,CUCURBITACIN I WITH HPLC,Cucurbitacin I hydrate,CUCURBITACIN I(SH),CUCURBITACIN I
Cucurbitacin Ia,Cucurbitacin F-25-acetate
Cucurbitacin A
Cucurbitacin L
Cucurbitacin F
dihydrocucurbitacin F
Cucurbitacin H,24-epi-Cucurbitacin G,Cucurbitacin G