L-(+)-발린

L-(+)-발린 속성

L-(+)-발린 MSDS

2-Aminoisovaleric acid

L-(+)-발린 C화학적 특성, 용도, 생산

순도시험

  (1) 용상 : 이 품목 0.5g을 물 20mL에 녹일 때, 그 액은 무색이며 그 탁도는 거의 징명 이하이어야 한다.

  (2) 액성 : 이 품목의 수용액(1→30)의 pH는 5.5～7.0이어야 한다.

  (3) 비선광도 : 이 품목을 105℃에서 3시간 건조한 다음 약 4g을 정밀히 달아 6N 염산에 녹여 50mL로 하여 이 액의 선광도를 측정할 때, ＝+26.5～+29.0° 이어야한다.

  (4) 비소 : 이 품목을 비소시험법에 따라 시험할 때, 그 양은 4.0ppm 이하이어야 한다.

  (5) 납 : 이 품목 5.0g을 취하여 원자흡광광도법 또는 유도결합플라즈마발광광도법에 따라 시험할 때, 그 양은 5.0ppm 이하이어야 한다.

  (6) 염화물 : 이 품목 0.5g을 취하여 염화물시험법에 따라 시험할 때, 그 양은 0.01N 염산 0.3mL에 대응하는 양 이하이어야 한다.

확인시험

  (1) 이 품목의 6N염산(1→25)은 우선성이다.

  (2) 이 품목의 수용액(1→1,000) 5mL에 닌히드린시액 1mL를 가하여 3분간 가열하면 적자～청자색을 나타낸다.

정량법

  「글리신」의 정량법에 따라 정량한다.

0.1N 과염소산용액 1mL ＝ 11.71mg C₅H₁₁NO₂

강열잔류물

  이 품목의 강열잔류물은 0.1% 이하이어야 한다.

개요

Valine (abbreviated as Val or V) is an α-amino acid with the chemical formula HO₂CCH(NH₂)CH(CH₃)₂. L-Valine is one of 20 proteinogenic amino acids. Its codons are GUU, GUC, GUA, and GUG. This essential amino acid is classified as nonpolar. Human dietary sources are any proteinaceous foods such as meats, dairy products, soy products, beans and legumes.
Along with leucine and isoleucine, valine is a branched-chain amino acid. It is named after the plant valerian. In sickle-cell disease, valine substitutes for the hydrophilic amino acid glutamic acid in hemoglobin. Because valine is hydrophobic, the hemoglobin is prone to abnormal aggregation.

화학적 성질

White or almost white, crystalline powder or colourless crystals, soluble in water, very slightly soluble in alcohol.

정의

ChEBI: The L-enantiomer of valine.

Biosynthesis

Valine is an essential amino acid, hence it must be ingested, usually as a component of proteins. It is synthesized in plants via several steps starting from pyruvic acid. The initial part of the pathway also leads to leucine. The intermediate α-ketoisovalerate undergoes reductive amination with glutamate. Enzymes involved in this biosynthesis include :
Acetolactate synthase
Acetohydroxy acid isomeroreductase
Dihydroxyacid dehydratase
Valine aminotransferase.

일반 설명

Valine is an essential amino acid, involved in the biosynthesis of glutamine and alanine. Valine being a branched-chain amino acid (BCAA), maintains a balance among the BCAAs. L-Valine serves as an energy fuel.

부작용

L-valine is a natural substance that is necessary for our health. As such, it generally does not have any side effects. However, taking large quantities of L-valine can cause fatigue, nausea, and a lack of muscle coordination.
Extremely high doses of L-valine can be dangerous. Excessive levels of L-valine can cause your body to produce excess ammonia which is toxic.
Extremely high levels of L-valine can cause your skin to tingle and can lead to hallucinations.

Safety Profile

Mutation data reported. When heated to decomposition it emits toxic fumes of NOx.

Purification Methods

Crystallise L-valine from water by addition of EtOH. It sublimes at 178-188o/0.03mm with 99.3% recovery and unracemised [Gross & Gradsky J Am Chem Soc 77 1678 1955]. [Perrin J Chm Soc 3125 1958, Greenstein & Winitz The Chemistry of the Amino Acids J. Wiley, Vol 3 pp 2368-23771961, Beilstein 4 IV 2659.]

L-(+)-발린 준비 용품 및 원자재

원자재

준비 용품

L-(+)-발린 공급 업체

공급자	전화	이메일	국가	제품 수	이점
Hangzhou Qiwei Pharmatech Co.,Ltd	13282840061	mw@qwpharmatech.com	China	109	58
Hebei Weibang Biotechnology Co., Ltd	+8615531157085	abby@weibangbio.com	China	8806	58
Shaanxi Dideu Medichem Co. Ltd	+86-29-81148696 +86-15536356810	1022@dideu.com	China	3882	58
Hebei Mujin Biotechnology Co.,Ltd	+86 13288715578 +8613288715578	sales@hbmojin.com	China	12832	58
Hebei Chuanghai Biotechnology Co,.LTD	+86-13131129325	sales1@chuanghaibio.com	China	5889	58
Suzhou Sanyi Polymer Chemical Technology Co., Ltd.	+8615571922873	15571922873@163.com	China	102	58
Shaanxi Haibo Biotechnology Co., Ltd	+undefined18602966907	qinhe02@xaltbio.com	China	997	58
Across Biotech Jinan Co LTD	+8613031735486	frank@acrossbiotech.com	China	105	58
Shaanxi Franta Biotechnology Co., Ltd	+86-13082019107 +86-13082019107	admin@flanderff.com	China	244	58
Hebei Saisier Technology Co., LTD	+86-18400010335 +86-18034520335	admin@hbsaisier.cn	China	1015	58

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