SANGUINARINE
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SANGUINARINE 속성
- 녹는점
- 205-215°C
- 끓는 점
- 483.53°C (rough estimate)
- 밀도
- 1.3463 (rough estimate)
- 굴절률
- 1.5180 (estimate)
- 저장 조건
- Keep in dark place,Sealed in dry,Room Temperature
- 용해도
- 클로로포름 (약간 용해됨), DMSO (약간 용해됨)
- 물리적 상태
- 고체
- 물리적 상태
- 단단한 모양
- 색상
- 하얀색
- LogP
- -0.653 (est)
안전
위험 카페고리 넘버 | 25 | ||
---|---|---|---|
안전지침서 | 13-45 | ||
유엔번호(UN No.) | 1544 | ||
독성 | LD50 oral in rat: 1660mg/kg |
SANGUINARINE C화학적 특성, 용도, 생산
개요
A naphthoisoquinoline alkaloid, this base occurs in the roots of Chelidonium majus L., Glaucium fimbrilligerum and Sanguinaria canadensis L. The alkaloid was stated by Schmidt, Konig and Tietz to crystallize from EtOH or AcOEt as colourless needles, m.p. 213°C but this low melting point was found to be due to the presence of chelerythrine as an impurity. Once this is removed as the pseudocyanide, the base crystallizes from Et20 and has the above melting point or 242-3°C on slow heating. Obtained from EtOH it forms the alcoholate, m.p. 195-7°C. The hydrochloride forms long, slender, bloodred needles. On distillation with Zn dust, the alkaloid furnishes a-naphthaphenanthridine and the structure given above has been further confirmed by synthesis.용도
Sanguinarium induces HO-1 expression thus inhibiting MMP-9 and COX-2 expression in TPA-induced breast cancer cells.정의
Sanguinarine is a benzophenanthridine alkaloid derived from the root of Sanguinaria canadendid. Limited available evidence indicates that it may be used to prevent and treat UV-induced skin damage. Specifically, topical application of sanguinarine on the skin of SKH-1 hairless mice before or after UVB irradiation resulted in significantly lower UVB-mediated skin edema, skin hyperplasia and infiltration of leukocytes, and markers of oxidative stress (e.g., H2O2).참고 문헌
Dana., Mag. Pharm., 23, 125 (1829)Bruchhausen, Bersch., Ber., 63, 2520 (1930)
Spath, Kuffner., ibid, 64, 370, 1123, 2034 (1931)
Synthesis:
Dyke, Moon, Sainsbury., Tetrahedron Lett., 3933 (1968)
SANGUINARINE 준비 용품 및 원자재
원자재
준비 용품
SANGUINARINE 공급 업체
글로벌( 226)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
---|---|---|---|---|---|
Changsha Staherb Natural Ingredients Co., Ltd. | +86-0731-84213302 +86-18374838656 |
info@staherb.cn | China | 1025 | 58 |
Shaanxi Haibo Biotechnology Co., Ltd | +undefined18602966907 |
qinhe02@xaltbio.com | China | 1000 | 58 |
Frapp's ChemicalNFTZ Co., Ltd. | +86 (576) 8169-6106 |
sales@frappschem.com | China | 885 | 50 |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 |
info@tianfuchem.com | China | 21663 | 55 |
Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 |
fandachem@gmail.com | China | 9284 | 55 |
Nanjing Finetech Chemical Co., Ltd. | 025-85710122 17714198479 |
sales@fine-chemtech.com | CHINA | 885 | 55 |
Shanghai Zheyan Biotech Co., Ltd. | 18017610038 |
zheyansh@163.com | CHINA | 3620 | 58 |
career henan chemical co | +86-0371-86658258 +8613203830695 |
sales@coreychem.com | China | 29888 | 58 |
Chengdu GLP biotechnology Co Ltd | 028-87075086 13350802083 |
scglp@glp-china.com | CHINA | 1824 | 58 |
Chengdu Biopurify Phytochemicals Ltd. | +8618080483897 |
sales@biopurify.com | China | 3772 | 58 |
SANGUINARINE 관련 검색:
페루라산
JATRORRHIZINE HCL(RG)
Coptisine chloride
CUCURBITACIN IIA
Berberine
Celastrus angulatus
Spatholobi Caulis
Capillary Wormwood Herb Extract
Sanguinarine citrate
chelerythrine chloride-sanguinarine chloride mixt.
SANGUINARINE HCl hplc,SANGUINARINE(SH),SANGUINARINE CHLORIDE,SANGUINARINE HCL
SANGUINARINE CHLORIDE(RG)
Ethoxysanguinarine
DIHYDROSANGUINARINE(P)
SANGUINARINE NITRATE,SANGUINARINE NITRATE(RG)
SANGUINARINE CHLORIDE HYDRATE
SANGUINARINE SULFATE
SANGUINARINE HCL DIHYDRATE