N-오메가-프로필-L-아르기닌

N-오메가-프로필-L-아르기닌
N-오메가-프로필-L-아르기닌 구조식 이미지
카스 번호:
137361-05-8
한글명:
N-오메가-프로필-L-아르기닌
동의어(한글):
N-오메가-프로필-L-아르기닌
상품명:
N-OMEGA-PROPYL-L-ARGININE
동의어(영문):
N-PLA;NΩZinc01546170;N-alpha,Nω-dimethyl-Nω-PROPYL-L-ARGININE;-bis-Boc-D-arginine;NW-PROPYL-L-ARGININE;NG-PROPYL-L-ARGININE;Nω-Propyl-L-Arginine
CBNumber:
CB3410297
분자식:
C9H20N4O2
포뮬러 무게:
216.28
MOL 파일:
137361-05-8.mol

N-오메가-프로필-L-아르기닌 속성

녹는점
198-200?C
끓는 점
366.5±52.0 °C(Predicted)
밀도
1.24±0.1 g/cm3(Predicted)
저장 조건
Desiccate at RT
용해도
클로로포름(약간 용해됨), 메탄올(약간 용해됨)
산도 계수 (pKa)
2.50±0.24(Predicted)
물리적 상태
흰색 내지 회백색 고체.
색상
하얀색
안정성
흡습성이 매우 높음
CAS 데이터베이스
137361-05-8(CAS DataBase Reference)

안전

N-오메가-프로필-L-아르기닌 C화학적 특성, 용도, 생산

개요

Nω-Propyl-L-Arginine is a potent and selective inhibitor of neuronal nitric oxide synthase (nNOS). Nω-Propyl-L-Arginine is a competitive inhibitor of bovine nNOS having a Ki value of 57 nM. The Ki values for eNOS (bovine) and iNOS (murine) are 8.5 and 180 μM, respectively. Nω-propyl-L-Arginine therefore exhibits 3,000-fold and 150-fold selectivity for the neuronal isoform versus the inducible (murine) and endothelial (bovine) isoforms of NOS, respectively.

화학적 성질

Off-White Solid

용도

A highly selective competitive inhibitor and inactivator of all three isoforms of NOS.

생물학적 활성

Highly selective and potent inhibitor of nNOS (K i = 57 nM). Displays 3158-fold and 149-fold selectivity over iNOS and eNOS respectively. Hypotensive in vivo .

N-오메가-프로필-L-아르기닌 준비 용품 및 원자재

원자재

준비 용품


N-오메가-프로필-L-아르기닌 공급 업체

글로벌( 65)공급 업체
공급자 전화 이메일 국가 제품 수 이점
Alchem Pharmtech,Inc.
8485655694
sales@alchempharmtech.com United States 63711 58
CONIER CHEM AND PHARMA LIMITED
+8618523575427
sales@conier.com China 49391 58
Career Henan Chemica Co
+86-0371-86658258 15093356674;
laboratory@coreychem.com China 30254 58
Dayang Chem (Hangzhou) Co.,Ltd.
571-88938639 +8617705817739
info@dycnchem.com China 52861 58
Nextpeptide Inc
+86-0571-81612335 +8613336028439
sales@nextpeptide.com China 19915 58
Hangzhou MolCore BioPharmatech Co.,Ltd.
+86-057181025280; +8617767106207
sales@molcore.com China 49739 58
GIHI CHEMICALS CO.,LIMITED
+8618058761490
info@gihichemicals.com China 49999 58
Aladdin Scientific
+1-+1(833)-552-7181
sales@aladdinsci.com United States 52927 58
Mainchem Co., Ltd. +86-0592-6210733
sale@mainchem.com China 32360 55
J & K SCIENTIFIC LTD. 010-82848833 400-666-7788
jkinfo@jkchemical.com China 94786 76

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