피부(또는 머리카락)에 묻으면 오염된 모든 의복은 벗거나 제거하시오 피부를 물로 씻으시오/샤워하시오.
P305+P351+P338
눈에 묻으면 몇 분간 물로 조심해서 씻으시오. 가능하면 콘택트렌즈를 제거하시오. 계속 씻으시오.
1-클로로-1-메틸실라사이클로부탄 C화학적 특성, 용도, 생산
물리적 성질
bp 103°C; d 0.985 g cm?3.
용도
Siletanes (silacyclobutanes) represent a unique
class of silicon-based reagents that have enjoyed much success in
a number of synthetic applications including aldol reactions, allylations,
cross-coupling reactions, carbosilane oxidations, and ring
expansions. The manifestation of their strain in enhanced Lewis
acidity and in the ring opening to silanols accounts for their utility.
1-Chloro-1-methylsiletane can be used for the preparation of the
various siletane derivatives for these applications. Grignard reagents react efficiently with 1-chloro-1-methylsiletane
to provide the corresponding aryl-, alkenyl-, or alkylsiletanes
(eqs 1–3).On the contrary, reactions with alkyllithiums are
limited to the reaction of 1 with a lithium acetylide (eq 4).The
reaction of 1 with an intermediate vinylalane obtained by hydroalumination
of 1-heptyne gave (E)-1-heptenylmethylsiletane
in >99/1 isomeric purity (eq 5).The reaction of 1 with LiAlD4
afforded 1-deuterio-1-methylsiletane (eq 6).
제조 방법
siletane can be prepared in large quantities
byWurtz coupling reaction of dichloro-3-chloropropylmethylsilane
with Mg.It is commercially available from Gelest
and Aldrich chemical company.
