Anti-von Willebrand Factor antibody produced in rabbit has been used for:
western blot analysis and immunostaining
immunocytochemistry
immunohistochemistry
indirect immunofluorescence
일반 설명
Human von Willebrand factor (factor VIII R:Ag) is a 270 kDa multimeric plasma gylcoprotein. The von Willebrand factor has functional binding domains to platelet glycoprotein Ib, glycoprotein IIb/IIIa, collagen and heparin. The factor is synthesized by endothelial cells and is also present in platelets and megakaryocytes.
Biochem/physiol Actions
It mediates platelet adhesion to injured vessel walls and serves as a carrier and stabilizer for coagulation factor VIII.
