니리다졸
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니리다졸 속성
- 녹는점
- 260-262°
- 밀도
- 1.561 (estimate)
- 굴절률
- 1.6200 (estimate)
- 물리적 상태
- 고체
- 물리적 상태
- 단단한 모양
- 산도 계수 (pKa)
- 12.73±0.20(Predicted)
- 색상
- DMF/MeOH의 황색 결정
- 수용성
- 0.13g/L(25℃)
- IARC
- 2B (Vol. 13, Sup 7) 1987
안전
유해 물질 데이터 | 61-57-4(Hazardous Substances Data) | ||
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독성 | TDLo orl-rat: 8 g/kg/90W-I:NEO CALEDQ 4,305,78 orl-rat LD50:900 mg/kg FAZMAE 17,108,73 |
니리다졸 C화학적 특성, 용도, 생산
용도
Antischistosomal.Pharmacology
Niridazole exhibits schistosomicide and amebicidal action. The mechanism of action is not known. It seems likely that it is concentrated in the parasite organism, which causes inhibition of phosphorylase activation, which is expressed in the depletion of glycogen reserves.It also may inhibit spermatogenesis of parasites by affecting the production of eggs. It is used for diseases caused by Dracunculus meddinesis, as well as Shistosoma haematobium and Shistosoma mansoni. It belongs to a group of tertiary drugs and is used only in the absence of the drug of choice. Synonyms of this drug are ambilhar and others.
Safety Profile
Confirmed carcinogen with experimental carcinogenic and neoplastigenic data. Poison by intraperitoneal route. Moderately toxic by ingestion. Experimental reproductive effects. Human mutation data reported. Used as an amoebicide and schistosomicidal agent.니리다졸 준비 용품 및 원자재
원자재
준비 용품
니리다졸 공급 업체
글로벌( 7)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
---|---|---|---|---|---|
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 |
info@tianfuchem.com | China | 21667 | 55 |
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 |
marketing@targetmol.com | United States | 19892 | 58 |
Alfa Chemistry | 1-516-6625404 |
support@alfa-chemistry.com | United States | 9171 | 60 |
TargetMol Chemicals Inc. | 4008200310 |
marketing@tsbiochem.com | China | 23962 | 58 |