비미놀

비미놀
비미놀 구조식 이미지
카스 번호:
21363-18-8
한글명:
비미놀
동의어(한글):
비미놀
상품명:
viminol
동의어(영문):
Z-424;viminol;Diviminol;Brn 0444219;Einecs 244-347-8;1-(alpha-(N-o-Chlorobenzyl)pyrryl)-2-di-sec-butylaminoethanol;1-[1-(2-Chlorobenzyl)-1H-pyrrol-2-yl]-2-(di-sec-butylamino)ethanol;1-(2-Chlorobenzyl)-alpha-((di-sec-butylamino)methyl)pyrrol-2-methanol;1-(o-Chlorobenzyl)-α-[(di-sec-butylamino)methyl]-1H-pyrrole-2-methanol;1-(o-Chlorobenzyl)-alpha-((di-sec-butylamino)methyl)pyrrole-2-methanol
CBNumber:
CB3938496
분자식:
C21H31ClN2O
포뮬러 무게:
362.942
MOL 파일:
21363-18-8.mol

비미놀 속성

끓는 점
bp0.1 mm 160-165°
밀도
1.07±0.1 g/cm3(Predicted)
산도 계수 (pKa)
14.38±0.20(Predicted)

안전

비미놀 C화학적 특성, 용도, 생산

Originator

Dividol ,Zambon ,Italy ,1974

Manufacturing Process

10 g (0.0278 mol) of 1-(o-chloro)-benzyl-2-di-sec-butylaminoacetyl-pyrrole and 300 ml of anhydrous diethyl ether are placed in a 500 ml four-necked flask with a mercury-sealed stirrer, a thermometer, a dropping funnel and a reflux condenser topped with a tube containing anhydrous calcium chloride. The solution is stirred and a mixture of 1g (0.0264 mol) of lithium aluminum hydride in 20 ml of diethyl ether is added slowly through the dropping funnel at such a rate that the solvent refluxes gently without external heating. When the addition is complete and the initial reaction subsides, the mixture is stirred and heated at gentle reflux for two hours.
The mixture is cooled and the excess of lithium aluminum hydride is decomposed with cracked ice. The water layer is separated and washed with diethyl ether. The combined ether extracts are dried over anhydrous magnesium sulfate and the solvent is removed by distillation under reduced pressure. Yield, 8.8 g; boiling point, 160°C to 165°C/0.1 mm Hg.

Therapeutic Function

Analgesic

비미놀 준비 용품 및 원자재

원자재

준비 용품


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