ChemicalBook >제품 카탈로그 >4하이드록시타목시펜

4하이드록시타목시펜

4하이드록시타목시펜 구조식 이미지

카스 번호:: 82413-23-8

한글명:: 4하이드록시타목시펜

동의어(한글):: 4하이드록시타목시펜

상품명:: 4Hydroxy Tamoxifen

동의어(영문):: 4’-hydroxy Tamoxifen;4'-Hydroxy TaMoxifen (contains up to 10% E isoMer);Tamoxifen Citrate Impurity 13 (4'-Hydroxytamoxifen);4-[(1Z)-1-[[4-[2-(Dimethylamino)ethoxy]phenyl]phenylmethylene]propyl]phenol;Phenol, 4-[(1Z)-1-[[4-[2-(dimethylamino)ethoxy]phenyl]phenylmethylene]propyl]-

CBNumber:: CB41175806

분자식:: C26H29NO2

포뮬러 무게:: 387.51

MOL 파일:: 82413-23-8.mol

속성

안전

용도

공급 업체 25

4하이드록시타목시펜 속성

녹는점: 150-153°C

끓는 점: 514.4±50.0 °C(Predicted)

밀도: 1.092±0.06 g/cm3(Predicted)

저장 조건: Amber Vial, -20°C Freezer, Under Inert Atmosphere

용해도: 클로로포름 (약간 용해됨), 디클로로메탄, 메탄올 (약간 용해됨)

물리적 상태: 고체

물리적 상태: 단단한 모양

산도 계수 (pKa): 10.32±0.15(Predicted)

색상: 흰색에서 황백색까지

안정성: 감광성

안전

4하이드록시타목시펜 C화학적 특성, 용도, 생산

개요

4’-hydroxy Tamoxifen is one of five main phase I metabolites of tamoxifen , a well-known estrogen receptor antagonist in breast but partial estrogen receptor agonist in endometrium. 4’-hydroxy Tamoxifen is a product of cytochrome P450 (CYP)2D6 and CYP2B6 activity. With the addition of a hydroxyl group, 4’-hydroxy tamoxifen has been shown to have a higher affinity for estrogen receptors compared to tamoxifen. At 10-100 μM, 4’-hydroxy tamoxifen is cytotoxic, in a non-apoptotic manner, to HEC-1B and HEC-1A human endometrial adenocarcinoma cell lines.

화학적 성질

White Solid

용도

A metabolite of Tamoxifen (T006000).

4하이드록시타목시펜 준비 용품 및 원자재

원자재

준비 용품

4하이드록시타목시펜 공급 업체

글로벌( 25)공급 업체

공급자	전화	이메일	국가	제품 수	이점
Hubei Jusheng Technology Co.,Ltd.	18871490254	linda@hubeijusheng.com	CHINA	28172	58
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	32165	58
Shenzhen Excellent Biomedical Technology Co.,Ltd.	+86-0755-26050679 +86-15915472436	sale@ex-biotech.cn	China	1031	58
Shanghai Boyle Chemical Co., Ltd.	021-50182298 021-50180596	sales@boylechem.com	China	2208	55
J & K SCIENTIFIC LTD.	010-82848833 400-666-7788	jkinfo@jkchemical.com	China	96815	76
Chemsky（shanghai）International Co.,Ltd.	021-50135380	shchemsky@sina.com	China	32321	50
BOC Sciences	1-631-485-4226; 16314854226	info@bocsci.com	United States	14055	65
Clearsynth Labs Limited	+91-22-26355700	info@clearsynth.com	India	9679	58
BOC Sciences	16314854226	info@bocsci.com	United States	9923	65
Shenzhen Polymeri Biochemical Technology Co., Ltd.	+86-400-002-6226 +86-13028896684;	sales@rrkchem.com	China	57412	58

4하이드록시타목시펜 관련 검색:

N-Desmethyl-4-hydroxy Tamoxifen (approx. 1:1 E/Z Mixture) Tamoxifen Impurity 3 4-Benzyloxy β-Hydroxy TaMoxifen TaMoxifen DiMer 1-(4-(2-Dimethylamino)-2-ethoxyphenyl butanone N-Desmethyl-4-hydroxy Tamoxifen β-D-Glucuronide (E/Z Mixture) Tamoxifen EP Impurity D (E)-4-Alloxycarboxyl Tamoxifen Endoxifen desdimethyltamoxifen TAMOXIFEN-N-OXIDE Droloxifene (E)-4-Acetoxy Tamoxifen N-Desmethyl Tamoxifen Methanethiosulfonate 2-[4-[(E)-1,2-diphenylbut-1-enyl]phenoxy]-N,N-dimethyl-ethanamine alpha-[4-[2-(dimethylamino)ethoxy]phenyl]-beta-ethyl-alpha-phenylphenethyl alcohol (E)-4-Hydroxy-N-desmethyl Tamoxifen (E/Z)-Tamoxifen