에리스로마이신A메톡심

에리스로마이신A메톡심
에리스로마이신A메톡심 구조식 이미지
카스 번호:
53066-26-5
한글명:
에리스로마이신A메톡심
동의어(한글):
에리스로마이신A메톡심
상품명:
Lexithromycin
동의어(영문):
Wy 48314;Lexithromycin;Erythromycin A-E-oxime;Azithromycin Impurity 4;Azithromycin Impurity 31;erythromycin A methoxime;Erythromycin A 9-Methoxime;Erythromycin, 9-(O-methyloxime);9-(Methoxyimino)-9-deoxoerythromycin;ErythroMycin A 9-MethoxiMe, Wy 48314
CBNumber:
CB41327717
분자식:
C38H70N2O13
포뮬러 무게:
762.97
MOL 파일:
53066-26-5.mol

에리스로마이신A메톡심 속성

녹는점
>115°C (dec.)
끓는 점
824.6±75.0 °C(Predicted)
밀도
1.26±0.1 g/cm3(Predicted)
저장 조건
Hygroscopic, -20°C Freezer, Under inert atmosphere
용해도
클로로포름 (약간 용해됨), DMSO (약간 용해됨)
산도 계수 (pKa)
13.19±0.70(Predicted)
물리적 상태
고체
물리적 상태
단단한 모양
색상
흰색에서 황백색까지
안정성
흡습성

안전

에리스로마이신A메톡심 C화학적 특성, 용도, 생산

개요

Lexithromycin is a semisynthetic antibiotic derived from erythromycin . Lexithromycin has improved absorption in vivo over erythromycin due to increased hydrophopicity and pH stability. As with other macrolides, lexithromycin prevents protein synthesis by binding the ribosome at the polypeptide exit tunnel. Formulations containing lexithromycin were tested in clinical trials as treatment for HIV but were discontinued.

용도

Lexithromycin is an early semi-synthetic erythromycin, prepared by reaction of the 9-keto moiety to methyl oxime. The structural change improves the pH stability profile and hydrophobicity of lexithromycin for better in vivo absorption. This same rationale was used to greater effect with roxithromycin and, as a result, lexithromycin was quickly superseded and has not been not extensively studied. Like all tetracyclines, lexithromycin shows broad spectrum antibacterial and antiprotozoan activity and acts by binding to the 30S and 50S ribosomal sub-units, blocking protein synthesis.

에리스로마이신A메톡심 준비 용품 및 원자재

원자재

준비 용품


에리스로마이신A메톡심 공급 업체

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Standardpharm Co. Ltd.
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TargetMol Chemicals Inc.
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ANHUI WITOP BIOTECH CO., LTD
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China National Standard Pharmaceutical Corporation Limited
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S.Z. PhyStandard Bio-Tech. Co., Ltd. 0755-4000505016 13380397412
3001272453@qq.com China 4963 50
ChemStrong Scientific Co.,Ltd 0755-0755-66853366 13670046396
sales@chem-strong.com China 18018 56
Shanghai Kewel Chemical Co., Ltd. 021-64609169 18901607656
greensnown@163.com China 9911 50

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