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toddalolactone C화학적 특성, 용도, 생산
개요
Toddalia aculeata Pers. (Rutaceae) contains, in addition to Berberine (q.v.), two
closely related alkaloids. This particular base forms colourless crystals from
CHC13 and is characterized as the hydrochloride monohydrate, m.p. 205-6°C;
nitrate, yellow needles, m.p. 239° C (dec.) and the picrate, glancing needles,
m.p. 237-8°C. Two methoxyl groups and a methylimino group have been
shown to be present.
용도
Toddalolactone is a prenylated coumarin which acts as a natural phosphodiesterase-4 inhibitor. Antiplasmodial and larvicidal agent.
