SOLANOCAPSINE

SOLANOCAPSINE 구조식 이미지
카스 번호:
상품명:
SOLANOCAPSINE
동의어(영문):
SOLANOCAPSINE
CBNumber:
CB41414217
분자식:
C27H46N2O2
포뮬러 무게:
0
MOL 파일:
Mol file

SOLANOCAPSINE 속성

녹는점
222°C

안전

SOLANOCAPSINE C화학적 특성, 용도, 생산

개요

A hex acyclic steroidal alkaloid first obtained from the berries of Solanum pseudo_x0002_capsicum L., and later from other Solanum species. The base crystallizes from 50% EtOH in flat prisms and has [α]D + 25.5° or + 24° (MeOH). The dihydrochloride monohydrate forms needles, m.p. > 280°C; the sulphate, flat colourless prisms, m.p. 324°C; the oxalate, m.p. 288-9°C; picrate, m.p. 194°C; diacetyl derivative, an amorphous powder, m.p. 193-6°C and the trimethyl compound, m.p. 209°C. The nitro so derivative has been prepared with m.p. 194°C. In contrast to most of the Solanum alkaloids, this base does not give a sparingly soluble digitonide.
Watt and his colleagues have stated that the alkaloid induces marked local irritation when injected intravenously. The systematic action is entirely intracardiac, the effects being mainly on the sinus. Large doses disturb conduction and disorganize the action of the heart.

참고 문헌

Breyer-Brandwyk., Bull. Sci. Pharmacol., 36,541 (1929)
Barger, Fraenkel-Conrat., 1. Chem. Soc., 1537 (1936)
Rochelmeyer, Stiitzel., Arch. Pharm., 282,92 (1944)
Schlittler, Uehlinger., Helv. Chim. Acta, 35,2034 (1952)
Schreiber, Ripperger., Z. Naturforsch., 17b, 217 (1962)
Schreiber, Ripperger., Annalen, 655, 114 (1962)
Budzikiewicz., Tetrahedron, 20,2267 (1964)
Nagai, Sato., Tetrahedron Lett., 2911 (1970)

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준비 용품


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