5-chloro-3-ethyl-1H-indole-2-carboxylic acid [2-(4-piperidin-1-yl-phenyl)-ethyl]-amide

5-chloro-3-ethyl-1H-indole-2-carboxylic acid [2-(4-piperidin-1-yl-phenyl)-ethyl]-amide 구조식 이미지
카스 번호:
868273-06-7
상품명:
5-chloro-3-ethyl-1H-indole-2-carboxylic acid [2-(4-piperidin-1-yl-phenyl)-ethyl]-amide
동의어(영문):
CS-412;Org 27569;ORG 27569;ORG-27569;Org27569 Cannabinoid CB1 receptor allosteric modulator Org-27569;Org27569,Inhibitor,Org-27569,Cannabinoid Receptor,Org 27569,inhibit;N-(4-(piperidin-1-yl)phenethyl)-5-chloro-3-ethyl-1H-indole-2-carboxamide;5-Chloro-3-ethyl-N-(4-(piperidin-1-yl)phenethyl)-1H-indole-2-carboxamide;5-Chloro-3-ethyl-N-[2-[4-(1-piperidinyl)phenyl]ethyl-1H-indole-2-carboxamide;1H-Indole-2-carboxamide,5-chloro-3-ethyl-N-[2-[4-(1-piperidinyl)phenyl]ethyl]-;Org27569 5-Chloro-3-ethyl-N-[2-[4-(1-piperidinyl)phenyl]ethyl-1H -indole-2-carboxamide
CBNumber:
CB42092872
분자식:
C24H28ClN3O
포뮬러 무게:
409.95
MOL 파일:
868273-06-7.mol

5-chloro-3-ethyl-1H-indole-2-carboxylic acid [2-(4-piperidin-1-yl-phenyl)-ethyl]-amide 속성

끓는 점
660.3±55.0 °C(Predicted)
밀도
1.218±0.06 g/cm3(Predicted)
저장 조건
2-8°C
용해도
H2O: <2mg/mL
산도 계수 (pKa)
14.87±0.30(Predicted)
물리적 상태
가루
색상
하얀색

안전

위험품 표기 Xn
위험 카페고리 넘버 22
WGK 독일 3

5-chloro-3-ethyl-1H-indole-2-carboxylic acid [2-(4-piperidin-1-yl-phenyl)-ethyl]-amide C화학적 특성, 용도, 생산

용도

Org 27569 is a drug that is a used in biological studies for structure-activity relationships of indole-carboxamides as CB1 receptor allosteric modulators.

생물학적 활성

Potent CB 1 receptor allosteric modulator (pEC 50 = 8.24). Significantly increases binding of the CB 1 agonist [ 3 H]CP 55.940 (pK b = 5.67) and decreases binding of the CB 1 inverse agonist [ 3 H]SR 141716A (pK b = 5.95). Inhibits CB 1 receptor antagonist efficacy in vitro (pK b = 7.57).

5-chloro-3-ethyl-1H-indole-2-carboxylic acid [2-(4-piperidin-1-yl-phenyl)-ethyl]-amide 준비 용품 및 원자재

원자재

준비 용품


5-chloro-3-ethyl-1H-indole-2-carboxylic acid [2-(4-piperidin-1-yl-phenyl)-ethyl]-amide 공급 업체

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5-chloro-3-ethyl-1H-indole-2-carboxylic acid [2-(4-piperidin-1-yl-phenyl)-ethyl]-amide 관련 검색:

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