PWM;Aids002201;Pwm-lectin;Aids-002201;POKEWEED MITOGEN;mitogens,pokeweed;Pokeweed mitogen, PWM;PHYTOLACCA AMERICANA LECTIN;PHYTOLACCA AMERICANA MITOGEN;PHYTOLACCA AMERICANA AGGLUTININ
Lectin from Phaseolus vulgaris (red kidney bean) has been used:
it has been used as a positive control to treat cells
to stimulate cell culture for the analysis of lymphocyte proliferation
to stimulate T cells
일반 설명
Lectins are proteins of plant origin, which have the ability to bind to certain neuronal surface glycoproteins and glycolipids. This ability of theirs helps them to be used as neuroanatomical tracers, as they are taken and transported in a retrograde or anterograde fashion.
Biochem/physiol Actions
Lectin agglutinates cells and precipitates polysaccharides and glycoproteins. It has anti-cancer, anti-human immunodeficiency virus (anti-HIV) and anti-microbial infection properties. Lectin is associated with toxic allergens and hemagglutinins. Lectin inhibits mucosal atrophy, lowers type 2 diabetes and obesity, enhances nutrient absorption and regulates drug targeting.
