4,4,5,5,5-Pentafluoro-1-pentanol
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4,4,5,5,5-Pentafluoro-1-pentanol 속성
- 끓는 점
- 62-64 °C35 mm Hg(lit.)
- 밀도
- 1.35 g/mL at 25 °C(lit.)
- 증기압
- 1.1-155.2hPa at 25-80.3℃
- 굴절률
- n
20/D 1.33(lit.)
- 인화점
- 145 °F
- 저장 조건
- 2-8°C
- 용해도
- 클로로포름에 용해됨
- 산도 계수 (pKa)
- 14.77±0.10(Predicted)
- 물리적 상태
- 액체
- 색상
- 무색의
- InChI
- InChI=1S/C5H7F5O/c6-4(7,2-1-3-11)5(8,9)10/h11H,1-3H2
- InChIKey
- QROUUECTKRZFHF-UHFFFAOYSA-N
- SMILES
- C(O)CCC(F)(F)C(F)(F)F
- LogP
- 1.59 at 25℃ and pH7
- CAS 데이터베이스
- 148043-73-6(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
위험품 표기 | Xi,F | ||
---|---|---|---|
위험 카페고리 넘버 | 36-36/37/38 | ||
안전지침서 | 26-36 | ||
유엔번호(UN No.) | 1993 | ||
WGK 독일 | 2 | ||
위험 참고 사항 | Irritant | ||
위험 등급 | FLAMMABLE | ||
HS 번호 | 29055900 |
4,4,5,5,5-Pentafluoro-1-pentanol C화학적 특성, 용도, 생산
개요
4,4,5,5,5-Pentafluoro-1-pentanol (PFP; Pentafluoropentanol) is an essential building block primarily used in the commercial manufacture of the API. It is typically activated with a sulfonate leaving group and displaced selectively by the sulfur atom in 9-mercapto-1-nonanol to make 9-[(4,4,5,5,5-pentafluoropentyl)-thio]-1-nonanol (FVS). FVS is subsequently converted into a bromide and coupled with the steroid portion to make fulvestrant. First approved by the FDA in 2002, fulvestrant is a medication used to treat hormone receptor (HR)-positive metastatic breast cancer in postmenopausal women with disease progression.화학적 성질
Colorless to yellow liquid용도
4,4,5,5,5-Pentafluoro-1-pentanol may be used in the preparation of chlorine-capped telechelic poly(methyl methacrylate)s.일반 설명
4,4,5,5,5-Pentafluoro-1-pentanol, also known as pentafluoropentanol, is a perfluorous solvent.4,4,5,5,5-Pentafluoro-1-pentanol 준비 용품 및 원자재
원자재
준비 용품
4,4,5,5,5-Pentafluoro-1-pentanol 공급 업체
글로벌( 298)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
---|---|---|---|---|---|
Tianjin Huiren Chemtech Co., Ltd | +86-86-22-23707858 +86-86-13672008665 |
huirentech@foxmail.com | China | 171 | 58 |
Lewoo Pharmatech(Shanghai)Co.,Ltd | +86-15800805830 +86-15800805830 |
miao@lewoopharma.com.cn | China | 184 | 58 |
Liaoning Pharmaceutical Innovation Co., Ltd | +8616588669988 |
sales@pipharma.com.cn | China | 151 | 58 |
Hebei Zhuanglai Chemical Trading Co.,Ltd | +8613343047651 |
admin@zlchemi.com | China | 3002 | 58 |
Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 |
sales@capotchem.com | China | 29798 | 60 |
Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 |
info@dakenam.com | China | 18652 | 58 |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 |
info@tianfuchem.com | China | 21667 | 55 |
Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 |
fandachem@gmail.com | China | 9338 | 55 |
Shanghai Yingrui Biopharma Co., Ltd. | +86-21-33585366 - 03@ |
sales03@shyrchem.com | CHINA | 738 | 60 |
Fluoropharm Co., Ltd. | +86-0571-85586753; +8613336034509 |
sales@fluoropharm.com | China | 1377 | 60 |
4,4,5,5,5-Pentafluoro-1-pentanol 관련 검색:
1-펜타놀
PERFLUOROPENTANOIC ACID
4,4,5,5,5-Pentafluoro-1-pentanethiol
ETHYL PENTAFLUOROPROPIONYLACETATE
4,4,5,5,5-Pentafluoro-1-pentanol
Fenipentol
ISOAMYL ALCOHOL
ALLYL PERFLUOROPENTANOATE
2,3,3,3-TETRAFLUORO-2-(PERFLUOROPENTOXY)PROPAN-1-OL
(NONAFLUORO-N-BUTYL)EPOXIDE
1H,1H-HEPTAFLUOROBUTYL EPOXIDE
PERFLUORO-2-TRIFLUOROMETHYL-4-OXANONANE
ETHYL PERFLUOROPENTANOATE
1H,1H-PERFLUOROPENTAN-1-OL
METHYL NONAFLUOROVALERATE
METHYL PENTAFLUOROPROPIONYLACETATE
2,2,3,3,4,4,5,5,5-NONAFLUOROPENTYL 2,5,7-TRINITRO-9-OXO-9H-FLUORENE-4-CARBOXYLATE
METHYL-3,3-DIMETHOXY-3-(PERFLUOROBUTYL)PROPANOATE