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ChemicalBook >제품 카탈로그 >화학 시약>유기 시약>크라운 에테르>1,4,7-Triazacyclononane

1,4,7-Triazacyclononane

1,4,7-Triazacyclononane 구조식 이미지
카스 번호:
4730-54-5
상품명:
1,4,7-Triazacyclononane
동의어(영문):
TACN;157715;1,4,7-triazonane;Triazacyclononane;TRIETHYLENETRIAMINE;1,4,8-Triazacyclononane;1,4,7-Triazacyclonomane;1,4,7-TRIAZACYCLONONANE;Triazacyclononanewhitextl;1,4,7-Triazacyclononane hcl
CBNumber:
CB4234922
분자식:
C6H15N3
포뮬러 무게:
129.2
MOL 파일:
4730-54-5.mol
MSDS 파일:
SDS

1,4,7-Triazacyclononane 속성

녹는점
42-45 °C (lit.)
끓는 점
110-130 °C/7 mmHg (lit.)
밀도
0.9987 (rough estimate)
굴절률
1.4620 (estimate)
인화점
>230 °F
저장 조건
2-8°C
수용성
물에 용해됨
용해도
클로로포름(약간 용해됨), 메탄올(약간 용해됨)
산도 계수 (pKa)
10.57±0.20(Predicted)
물리적 상태
수정 같은
색상
하얀색
BRN
773877
InChIKey
ITWBWJFEJCHKSN-UHFFFAOYSA-N
안전
  • 위험 및 안전 성명
  • 위험 및 사전주의 사항 (GHS)
위험품 표기 C
위험 카페고리 넘버 34
안전지침서 26-36/37/39-45
유엔번호(UN No.) UN 3259 8/PG 2
WGK 독일 3
F 고인화성물질 3-10-34
위험 등급 8
포장분류 III
HS 번호 2933998090
그림문자(GHS): GHS hazard pictograms
신호 어: Danger
유해·위험 문구:
암호 유해·위험 문구 위험 등급 범주 신호 어 그림 문자 P- 코드
H314 피부에 심한 화상과 눈에 손상을 일으킴 피부부식성 또는 자극성물질 구분 1A, B, C 위험 GHS hazard pictograms P260,P264, P280, P301+P330+ P331,P303+P361+P353, P363, P304+P340,P310, P321, P305+ P351+P338, P405,P501
예방조치문구:
P260 분진·흄·가스·미스트·증기·...·스프레이를 흡입하지 마시오.
P280 보호장갑/보호의/보안경/안면보호구를 착용하시오.
P303+P361+P353 피부(또는 머리카락)에 묻으면 오염된 모든 의복은 벗거나 제거하시오 피부를 물로 씻으시오/샤워하시오.
P305+P351+P338 눈에 묻으면 몇 분간 물로 조심해서 씻으시오. 가능하면 콘택트렌즈를 제거하시오. 계속 씻으시오.
P363 다시 사용전 오염된 의류는 세척하시오.
NFPA 704
1
3 0

1,4,7-Triazacyclononane C화학적 특성, 용도, 생산

개요

1,4,7-Triazacyclononane, known as "TACN" which is pronounced "tack-en," is a cyclic organic compound with the formula C6H12(NH)3. TACN is derived, formally speaking, from cyclononane by replacing three equidistant CH2 groups with NH groups. TACN is one of the oligomers derived from aziridine, C2H4NH. Other members of the series include diazacyclohexane, C4H8(NH)2, and the cyclic tetramer 1,4,7,10-tetraazacyclododecane.

화학적 성질

White - light yellow solid

용도

1,4,7-Triazacyclononane (TACN) is a versatile platform from which various ligands can be derived to form effective chelators for (radio)copper(II) complexation. The ability of TACN-derivatives to form highly stable complexes with copper(II) is greatly influenced by the number and type of substituents on the macrocyclic ring. The formed copper(II) complexes show a broad variability in their thermodynamic stability and kinetic inertness, varying in structure from square-pyramidal to distorted octahedral. TACN-based BFCAs have also been used for indirect radiolabelling of biomolecules, rendering them suitable for imaging and therapy.

제조 방법

The ligand is prepared from diethylene triamine as follows by macrocyclization using ethyleneglycol ditosylate.
H2NCH2CH2NHCH2CH2NH2 + 3 TsCl → Ts(H)NCH2CH2N(Ts)CH2CHH2N(H)Ts + 3 HCl Ts(H)NCH2CH2N(Ts)CH2CH2N(H)Ts + 2 NaOEt → Ts(Na)NCH2CH2N(Ts)CH2CH2N(Na)Ts Ts(Na)NCHH2CH2N(Ts)CH2CH2N(Na)Ts + TsOCH2CH2OTs + → [(CH2CH2N(Ts)]3 + 2 NaOTs [(CH2CH2N(Ts)]3 + 3 H2O → [CH2CH2NH]3 + 3 HOTs

주요 응용

Starting material for the synthesis of 1,4,7-trifunctionalized derivatives which have applications in metal complexation.
Possible reagent for compleximetric titrations with high cation-binding selectivity.

1,4,7-Triazacyclononane 준비 용품 및 원자재

원자재

준비 용품

6BH-2A,4A,6A-TRIAZACYCLOPENTA[CD]PENTALENE, HEXAHYDRO- (9CI)

1,4,7-Triazacyclononane 공급 업체

글로벌( 215)공급 업체
공급자 전화 이메일 국가 제품 수 이점
Shaanxi Dideu Medichem Co. Ltd 		18192627656
 1012@dideu.com China 3002 58
Capot Chemical Co.,Ltd. 		+86-（0）57185586718 +86-13336195806
 sales@capot.com China 29791 60
career henan chemical co 		+86-0371-86658258 +8613203830695
 sales@coreychem.com China 29885 58
Accela ChemBio Inc. 		+1-858-6993322
info@accelachem.com United States 19943 58
Hubei xin bonus chemical co. LTD 		86-13657291602
linda@hubeijusheng.com CHINA 22963 58
Chongqing Chemdad Co., Ltd 		+86-023-6139-8061 +86-86-13650506873
 sales@chemdad.com China 39894 58
Alchem Pharmtech,Inc. 		8485655694
sales@alchempharmtech.com United States 63687 58
Hefei TNJ Chemical Industry Co.,Ltd. 		+86-0551-65418671 +8618949823763
 sales@tnjchem.com China 34553 58
Hefei Hirisun Pharmatech Co., Ltd 		+8615056975894
 shawn@hirisunpharm.com CHINA 9911 58
Dayang Chem (Hangzhou) Co.,Ltd. 		571-88938639 +8617705817739
 info@dycnchem.com China 52849 58

1,4,7-Triazacyclononane 관련 검색:

노르말노난 1.4-다이옥세인 1,4,7-TRIMETHYL-1,4,7-TRIAZACYCLONONANE 1,4,7-Triazacyclononane trihydrochloride CYCLEN-GLYOXAL (p-SCN-Bn)-NOTA bis(N,N',N''-trimethyl-1,4,7-triazacyclononane)-trioxo-dimanganese (IV) di(hexafluorophosphate) monohydrate HEXABENZILISOVYURTSITAN 1,4,7-triazacyclononane-N,N',N''-triacetic acid 1,4,7-Triazacyclononane 3-[2-(Acetylamino)ethyl]-6,9-dimethyl-3,6,9-triazacyclononane 1,4,7-Triazacyclononane-1,4,7-triacetic acid,1,4,7-Triazacyclononane-1,4,7-trisacetic acid N,N',N''-tris(2-methyl-(2-mercaptopropyl))-1,4,7-triazacyclononane-pertechnetate N',N',N'-tris(2-methyl-2-mercaptopropyl)-1,4,7-triazacyclononane N,N,N',N',N'',N''-Hexamethyl-1,4,7-triazacyclononane-1,4,7-tripropionamide N,N,N',N',N'',N''-Hexamethyl-1,4,7-triazacyclononane-1,4,7-tri(acetamide) 1,4,7-triazacyclononane-N,N',N''-tris(methylenephosphonate monoethyl ester) 3-Benzyl-6,9-dimethyl-3,6,9-triazacyclononane,1-Benzyl-4,7-dimethyl-1,4,7-triazacyclononane,1,4-Dimethyl-7-benzyl-1,4,7-triazacyclononane
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