Melanotan-1
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Melanotan-1 속성
- 밀도
- 1.46±0.1 g/cm3(Predicted)
- RTECS 번호
- OS1830200
- 저장 조건
- −20°C
- 물리적 상태
- 고체
- 물리적 상태
- 단단한 모양
- 산도 계수 (pKa)
- 4.43±0.10(Predicted)
- 색상
- White to off-white
- 수용성
- Soluble to 0.60 mg/ml in sterile water
- 시퀀스
- Ac-Ser-Tyr-Ser-Nle-Glu-His-D-Phe-Arg-Trp-Gly-Lys-Pro-Val-NH2
- InChIKey
- UAHFGYDRQSXQEB-LEBBXHLNSA-N
- CAS 데이터베이스
- 75921-69-6(CAS DataBase Reference)
안전
WGK 독일 | 3 |
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Melanotan-1 C화학적 특성, 용도, 생산
용도
Melanotan 1 is a highly potent melanotropin with extended biological activity and resistance to enzymatic degredation by serum enzymes. [Nle4, D-Phe7]-α-Melanocyte Stimulating Hormone trifluoroacetate salt has been used to detect its effect on O2 consumption and CO2 production in C57BL/6 mice. It is also used to determine its effect on leptin secretion in the primary cultures of differentiated adipocytes.Origin
Melanotan 1, an alpha MSH analog (Nle4DPhe7-Melanocyte-Stimulating Hormone), is a potent melanocortin developed in the 1980s. Melanotan 2 is a shorter cyclic variant of Melanotan 1 produced in the 1990s. Melanotan 2 was found to increase skin pigmentation at lower cumulative doses than Melanotan 1. However, in clinical trials it was found to have more side effects including nausea somnolence and penile erections[1].일반 설명
[Nle4, D-Phe7]-α-melanocyte stimulating hormone is a potent analogue of α;-melanocyte-stimulating hormone (α -MSH). αMSH is a tridecapeptide, mostly produced by the cells in the brain, pituitary and in circulation.Biochem/physiol Actions
[Nle4, D-Phe7]-α-melanocyte stimulating hormone is 100 times more potent than α-MSH in stimulating melanoma tyrosinase, which is a rate limiting enzyme in melanin biosynthesis and is 26 times as potent as α-MSH in S91adenylate cyclase assay. α –MSH has an essential role to play in melanin production in animals. It also regulates development of several skin diseases, including cutaneous inflammation and hyper-proliferative skin diseases.부작용
The TGA has previously warned consumers against the use of Melanotan-I and Melanotan-II for tanning and weight loss. Side-effects include darkened skin, increased moles and freckles, nausea, vomiting, loss of appetite, flushing of the face, involuntary stretching and yawning, and spontaneous erections.Melanotan-1 준비 용품 및 원자재
원자재
준비 용품
Melanotan-1 공급 업체
글로벌( 248)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
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ZHEJIANG JIUZHOU CHEM CO., LTD | +86-0576225566889 +86-13454675544 |
admin@jiuzhou-chem.com;jamie@jiuzhou-chem.com;alice@jiuzhou-chem.com | China | 19947 | 58 |
Hebei Xinsheng New Material Technology Co., LTD. | +86-16632316109 |
xinshengkeji@xsmaterial.com | China | 1092 | 58 |
BOC Sciences | +1-631-485-4226 |
inquiry@bocsci.com | United States | 19553 | 58 |
zhuzhou dingcheng meihei comestic co.,ltd | +8618873369619 |
dingchengbusiness8@163.com | China | 260 | 58 |
Hebei Xunou new energy Technology Co., LTD | +undefined17531957005 |
xunou8@hbxunou.com | China | 36 | 58 |
Strong peptide cross-border e-commerce Co. LTD | +undefined13930052870 |
qt01@qiangtaipharm.com | China | 84 | 58 |
Shanghai Affida new material science and technology center | +undefined15081010295 |
admin@oudaxin.com | China | 114 | 58 |
Dorne Chemical Technology co. LTD | +86-86-13583358881 +8618560316533 |
Ethan@dornechem.com | China | 3147 | 58 |
Shanghai Yunao International Trade Co., Ltd | +8617621705551 |
asdf@shanghaihg.cn | China | 265 | 58 |
Wuhan senwayer century chemical Co.,Ltd | +undefined-27-86652399 +undefined13627115097 |
market02@senwayer.com | China | 890 | 58 |
Melanotan-1 관련 검색:
디에틸스틸베스트롤
D-Phenylalanine
Melanotan II),MT-I (a MSH)
ALPHA-MSH
Melanotan Ⅱ Actate,MelanotanⅡAcetate,Melanotan-II(MT-II),Melanotan II acetate salt,Mt-Ii(Melanotan),Melanotan 2,Melanotan Ц,MELANOTAN II
AC-LYS-PRO-VAL-NH2
MELANOTAN II, MT-Ⅱ
Melanotan,alpha-MSH
Melanotan II acetate
ALPHA-MSH
Melanotan 1
Melanotan Ⅱ
[Nle4, D-Phe7]alfa-MSH, Melanotan I
MELANOTAN II TRIFLUOROACETATE SALT
MelanotanⅠ(α-MSH)
Melanotan I acetate
AC-SYS(NLE)EH(D-PHE)RWGKPVK(BIOTIN)-AMIDE