AMG-51
|
|
AMG-51 속성
- 끓는 점
- 739.7±70.0 °C(Predicted)
- 밀도
- 1.33±0.1 g/cm3(Predicted)
- 산도 계수 (pKa)
- 7.01±0.10(Predicted)
안전
AMG-51 C화학적 특성, 용도, 생산
효소 저해제
This protein kinase inhibitor (FW = 629.65 g/mol; CAS 890019-63-3; Solubility: 15 mM in DMSO), also known as 5-(3-fluoro-4-(6-methoxy-7- (3-morpholinopropoxy)quinolin-4-yloxy)phenyl)-2-(4-fluorophenylamino)-3-methylpyrimidin-4(3H)-one, targets c-Met, or hepatocyte growth factor receptor (HGFR), a protein tyrosine kinase that plays a key role in several cellular processes and is overexpressed or mutated in different human cancers. AMG-51 shows the enzyme selectivity of c-Met with a (Ki = 4.9 nM), with off-targets, such as IGFR (Ki = 22nM), Ron or Recepteur d'Origine Nantais kinase (Ki = 28nM), and KDR (Ki = 139 nM).AMG-51 준비 용품 및 원자재
원자재
준비 용품
AMG-51 공급 업체
글로벌( 10)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| Amadis Chemical Company Limited | 571-89925085 |
sales@amadischem.com | China | 131980 | 58 |
| SYN|thesis med chem P/L | +86-021-50720296 |
service@synkinase.com | China | 266 | 58 |
| Pharmacodia (Beijing) Co.,Ltd | +86-400-851-9921 |
sales@pharmacodia.com | China | 2317 | 55 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 |
info@efebio.com | China | 9708 | 58 |
| Zhongshan Geometric Biological Technology Co., Ltd. | +86-13168912896 |
China | 253 | 58 | |
| Lynnchem | 86-(0)29-85992781 17792393971 |
info@lynnchem.com | China | 4587 | 58 |
| Novachemistry | 44-20819178-90 02081917890 |
info@novachemistry.com | United Kingdom | 4381 | 58 |
| Shanghai Biopharmaleader Co., Ltd. | +86 18721201413 |
sales@biopharmaleader.com | China | 1720 | 58 |
| Changzhou Furuisi Biotechnology Co., Ltd | 0519-85524369 |
3477467573@qq.com | China | 8618 | 58 |