TetroMycin A

TetroMycin A 구조식 이미지
카스 번호:
180027-83-2
상품명:
TetroMycin A
동의어(영문):
TetroMycin A;18H-16a,19-Metheno-16aH-benzo[b]naphth[2,1-j]oxacyclotetradecin-18,20(1H)-dione, 4-(acetyloxy)-2,3,4,4a,6a,9,10,12a,15,16,20a,20b-dodecahydro-21-hydroxy-1,6,7,11,12a,14,15,20a-octamethyl-, (1S,4S,4aS,6aR,7E,11E,12aR,15R,16aS,20aS,20bR)- (9CI)
CBNumber:
CB42703769
분자식:
C36H48O6
포뮬러 무게:
576.763
MOL 파일:
180027-83-2.mol

TetroMycin A 속성

끓는 점
684.1±55.0 °C(Predicted)
밀도
1.17±0.1 g/cm3(Predicted)
저장 조건
Store at -20°C
용해도
DMSO에 용해됨
물리적 상태
고체
물리적 상태
단단한 모양
산도 계수 (pKa)
4.50±1.00(Predicted)

안전

TetroMycin A C화학적 특성, 용도, 생산

용도

Tetromycin A is an unusual tetronic acid, structurally related to kijanimicin, chlorothricin, saccharocarcin, tetrocarcin and versipelostatin. Tetromycin A has pronounced activity against antibiotic susceptible and resistant Gram positive bacteria including MRSA. Limited availability has restricted further investigation of this metabolite in the literature. Several members of this class have received considerable literature focus. Versipelostatin inhibits transcription from the promoter of GRP78, a gene that is activated as part of a stress signalling pathway under glucose deprivation resulting in unfolded protein response (UPR). The UPR-inhibitory action is seen only in conditions of glucose deprivation and causes selective and massive killing of the glucose-deprived cells. Tetrocarcin A appears to target the phosphatidylinositide-3'-kinase/Akt signalling pathway.

TetroMycin A 준비 용품 및 원자재

원자재

준비 용품


TetroMycin A 공급 업체

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