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ALPHA-METHYL-P-[1-OXO-2-ISOINDOLINYL]-BENZENEACETIC ACID

ALPHA-METHYL-P-[1-OXO-2-ISOINDOLINYL]-BENZENEACETIC ACID 구조식 이미지

카스 번호:: 31842-01-0

상품명:: ALPHA-METHYL-P-[1-OXO-2-ISOINDOLINYL]-BENZENEACETIC ACID

동의어(영문):: k4277;flosin;Praxis;flosint;Bor-ind;Reumofe;isindone;Reumofene;INDOPROFEN;Aids025462

CBNumber:: CB4297426

분자식:: C17H15NO3

포뮬러 무게:: 281.31

MOL 파일:: 31842-01-0.mol

속성

안전

용도

공급 업체 80

ALPHA-METHYL-P-[1-OXO-2-ISOINDOLINYL]-BENZENEACETIC ACID 속성

녹는점: 213-214°

끓는 점: 423.97°C (rough estimate)

밀도: 1.1302 (rough estimate)

굴절률: 1.4500 (estimate)

저장 조건: 2-8°C

용해도: 메탄올(약간 용해됨,초음파 처리)

물리적 상태: Solid

산도 계수 (pKa): pKa 5.8 (Uncertain)

색상: White to off-white

안전

위험 및 안전 성명
위험 및 사전주의 사항 (GHS)

위험품 표기	T
위험 카페고리 넘버	25-40
안전지침서	22-36/37/39-45
유엔번호(UN No.)	UN 2811 6.1 / PGIII
WGK 독일	3
RTECS 번호	MU6645000
독성	LD50 in rats (mg/kg): 58.66 i.v.; 60.83 orally (Buttinoni)

그림문자(GHS):

신호 어:

Danger

유해·위험 문구:

암호	유해·위험 문구	위험 등급	범주	신호 어	그림 문자	P- 코드
H301	삼키면 유독함	급성 독성 물질 - 경구	구분 3	위험		P264, P270, P301+P310, P321, P330,P405, P501
H351	암을 일으킬 것으로 의심됨 (노출되어도 암을 일으키지 않는다는 결정적인 증거가 있는 노출경로가 있다면 노출경로 기재)	발암성 물질	구분 2	경고		P201, P202, P281, P308+P313, P405,P501

예방조치문구:

P201

사용 전 취급 설명서를 확보하시오.

ALPHA-METHYL-P-[1-OXO-2-ISOINDOLINYL]-BENZENEACETIC ACID C화학적 특성, 용도, 생산

화학적 성질

ALPHA-METHYL-P-[1-OXO-2-ISOINDOLINYL]-BENZENEACETIC ACID is Off-White Solid

용도

ALPHA-METHYL-P-[1-OXO-2-ISOINDOLINYL]-BENZENEACETIC ACID is a non-steroidal anti-inflammatory agent used for treatment of pain and inflammation

정의

ChEBI: A monocarboxylic acid that is propionic acid in which one of the hydrogens at position 2 is substituted by a 4-(1-oxo-1,3-dihydroisoindol-2-yl)phenyl group. Initially used as an anti-inflammatory and analgesic, it was withdrawn from the market due to causi g severe gastrointestinal bleeding. It has been subsequently found to increase production of the survival motor neuron protein.

World Health Organization (WHO)

Indoprofen, a nonsteroidal anti-inflammatory agent, was introduced in 1976 for the treatment of rheumatic disorders. By 1983 its use had been associated with serious adverse effects, some of which were fatal. This led to its withdrawal in the United Kingdom and Cyprus. In 1984 reports of intestinal tumours in rats led to the drug's temporary withdrawal in Germany and Italy. This was followed immediately by the suspension of marketing worldwide by the major manufacturer.

ALPHA-METHYL-P-[1-OXO-2-ISOINDOLINYL]-BENZENEACETIC ACID 준비 용품 및 원자재

원자재

에틸2-클로로메틸벤조에이트 수산화칼륨 Benzeneacetic acid, 4-(1,3-dihydro-1-oxo-2H-isoindol-2-yl)-α-methyl-, ethyl ester Benzeneacetic acid, 4-(1,3-dihydro-1-oxo-2H-isoindol-2-yl)-α-methyl-, methyl ester Benzeneacetic acid, 4-(1,3-dihydro-2H-isoindol-2-yl)-α-methyl-, ethyl ester 1H-Isoindol-1-one, 2-(4-chlorophenyl)-2,3-dihydro- 4-아미노히드라트로프산 에틸2-(4-아미노페닐)프로피오네이트 2-(4-니트로페닐)프로피온산 에틸2-(4-니트로페닐)프로피오네이트 아연 carbon monoxide 이산화탄소 2-카르복시벤즈알데히드

준비 용품

ALPHA-METHYL-P-[1-OXO-2-ISOINDOLINYL]-BENZENEACETIC ACID 공급 업체

글로벌( 80)공급 업체

공급자	전화	이메일	국가	제품 수	이점
Capot Chemical Co.,Ltd.	+86-（0）57185586718 +86-13336195806	sales@capot.com	China	29791	60
Hangzhou FandaChem Co.,Ltd.	+8615858145714	FandaChem@Gmail.com	China	9026	55
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49374	58
career henan chemical co	+86-0371-86658258 +8613203830695	factory@coreychem.com	China	29810	58
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	32161	58
TargetMol Chemicals Inc.		support@targetmol.com	United States	38631	58
Shanghai Acmec Biochemical Technology Co., Ltd.	+undefined18621343501	product@acmec-e.com	China	33338	58
Aladdin Scientific	+1-+1(833)-552-7181	sales@aladdinsci.com	United States	57505	58
TargetMol Chemicals Inc.	+8613564774135	zijue.cai@tsbiochem.com	United States	19885	58
SHANGHAI KEAN TECHNOLOGY CO., LTD.	+8613817748580	cooperation@kean-chem.com	China	40066	58

ALPHA-METHYL-P-[1-OXO-2-ISOINDOLINYL]-BENZENEACETIC ACID 관련 검색:

이부프로펜 Indole-3-carboxaldehyde Indoramin D5 Indacaterol Maleate Veratraldehyde Benyl propionic methyl ester DL-INDOLE-3-LACTIC ACID INDOMETHACIN ACYL-B-D-GLUCURONIDE 3-INDOXYL SULFATE POTASSIUM SALT Indole 4-(DIMETHYLAMINO)PHENYLACETIC ACID 4-(DIMETHYLAMINO)PHENETHYL ALCOHOL ALPHA-METHYL-P-[1-OXO-2-ISOINDOLINYL]-BENZENEACETIC ACID dexindoprofen Actarit Indobufen 4-ISOPROPYLACETANILIDE 4-Aminophenylacetic acid